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Advanced filters: Author: Spandan Chennamadhavuni Clear advanced filters

  • Macrocycles have the potential to act on currently undruggable targets, but their discovery thus far has been unsystematic. A physicochemical analysis of all nonredundant co-crystal structures now sets out guidelines for macrocycle development.

    • Elizabeth A Villar
    • Dmitri Beglov
    • Adrian Whitty
    Research
    Nature Chemical Biology
    Volume: 10, P: 723-731