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Showing 1–2 of 2 results
Advanced filters: Author: Sravanth K. Hindupur Clear advanced filters

  • The autophagic and Hippo pathways are both well characterized contributors to cancer. Here, Tang et al show that LATS1, but not LATS2, negatively regulates autophagy by promoting Beclin1 ubiquitination, which restricts lethal autophagy induced by sorafenib treatment in cancer cells.

    • Fengyuan Tang
    • Ruize Gao
    • Gerhard Christofori
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-17

  • Decreased expression of histidine phosphatase LHPP, a novel tumour suppressor, results in increased global histidine phosphorylation and hepatocellular carcinoma.

    • Sravanth K. Hindupur
    • Marco Colombi
    • Michael N. Hall
    Research
    Nature
    Volume: 555, P: 678-682