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Showing 1–4 of 4 results
Advanced filters: Author: Sridhar Raghavachari Clear advanced filters

  • The authors report that the rate at which calmodulin binds calcium is faster than that of other calcium binding proteins, and that calmodulin directly intercepts incoming calcium and sets [Ca2+]free rather than responding to the lower [Ca2+]free set by other buffers.

    • Guido C Faas
    • Sridhar Raghavachari
    • Istvan Mody
    Research
    Nature Neuroscience
    Volume: 14, P: 301-304

  • Synaptic transmission is temporally and spatially tightly regulated to serve the needs of fast information flow in the nervous system. Lisman and colleagues bridge the synaptic cleft and review the sequence of pre- and postsynaptic events of quantal release.

    • John E. Lisman
    • Sridhar Raghavachari
    • Richard W. Tsien
    Reviews
    Nature Reviews Neuroscience
    Volume: 8, P: 597-609

  • Long-term potentiation (LTP) describes the long-lasting increase in the strength of synaptic transmission between two neurons, a process that may be integral to learning and memory. In this Review, Lisman and colleagues examine the central role that calcium/calmodulin-dependent protein kinase II (CaMKII) has in this form of synaptic plasticity. Focusing on postsynaptic mechanisms, the authors discuss CaMKII in the context of both the early and late stages of LTP.

    • John Lisman
    • Ryohei Yasuda
    • Sridhar Raghavachari
    Reviews
    Nature Reviews Neuroscience
    Volume: 13, P: 169-182