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Advanced filters: Author: Srinivas D. Sithu Clear advanced filters

  • The microRNA miR-21 is overexpressed in cancer and is thought to function through anti-apoptotic activity. Here, Ma et al. show that deleting or blocking miR-21 in mice protects against acute pancreatitis and TNF-α-induced tissue damage by inhibiting RIP3-dependent regulated necrosis (necroptosis).

    • Xiaodong Ma
    • Daniel J. Conklin
    • Yong Li
    Research
    Nature Communications
    Volume: 6, P: 1-13