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Showing 1–17 of 17 results
Advanced filters: Author: Stéphanie Lacour Clear advanced filters

  • How the cortex generates movement to achieve different tasks remains poorly understood. Here the authors show that the cortex serializes motor control by first performing task-specific computations in dorsal premotor cortex in order to then generate task-independent commands in primary motor cortex.

    • Simon Borgognon
    • Nicolò Macellari
    • Grégoire Courtine
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18

  • Ultrathin and conformal piezoelectric transducers enable high-resolution mapping of the mechanical properties of human skin.

    • Stéphanie P. Lacour
    News & Views
    Nature Materials
    Volume: 14, P: 659-660

  • Water and ion ingress are challenging to quantify, especially in miniaturized microsystems. Here, Mariello et al. report a wireless and battery-free flexible water-permeation sensing platform, using backscatter communication and Mg-based microsensors for in-situ monitoring of implantable bioelectronics.

    • Massimo Mariello
    • James Daniel Rosenthal
    • Stéphanie P. Lacour
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • Bioelectronic interfacing with living tissues should match the biomechanical properties of biological materials to reduce damage to the tissues. Here, the authors present a fully viscoelastic microelectrode array composed of an alginate matrix and carbon-based nanomaterials encapsulated in a viscoelastic hydrogel for electrical stimulation and signal recording of heart and brain activities in vivo.

    • Christina M. Tringides
    • Nicolas Vachicouras
    • David J. Mooney
    Research
    Nature Nanotechnology
    Volume: 16, P: 1019-1029

  • The efficacy of epidural electrical stimulation (EES) to engage arm muscles and improve movement after spinal cord injury is still unclear. Here, the authors investigated how EES can recruit upper-limb motor neurons by combining computational modelling with experiments in non-human primates.

    • Nathan Greiner
    • Beatrice Barra
    • Marco Capogrosso
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-19

  • Peripheral nerves have a complex physiology and it is therefore difficult to measure axonal activity in vitro. Here the authors make a nerve-on-a-chip platform to align peripheral nerves and permit measurement of conduction amplitude and velocity along several axons in a single experiment.

    • Sandra Gribi
    • Sophie du Bois de Dunilac
    • Stéphanie P. Lacour
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10

  • Transcriptomic analysis following epidural electrical stimulation of the lumbar spinal cord during neurorehabilitation in mice identifies a population of neurons that orchestrates the restoration of walking following paralysis.

    • Claudia Kathe
    • Michael A. Skinnider
    • Grégoire Courtine
    ResearchOpen Access
    Nature
    Volume: 611, P: 540-547

  • Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

    • Céline Bellenguez
    • Fahri Küçükali
    • Jean-Charles Lambert
    ResearchOpen Access
    Nature Genetics
    Volume: 54, P: 412-436

  • Metallic glasses possess intriguing functional properties, but controlled fabrication with nanoscale feature sizes remains challenging. Thermal co-drawing within a viscosity-matched polymer matrix enables the fabrication of uniform metallic glass fibres with feature sizes down to a few tens of nanometres, arbitrary transverse geometries and aspect ratios greater than 1010.

    • Wei Yan
    • Inès Richard
    • Fabien Sorin
    Research
    Nature Nanotechnology
    Volume: 15, P: 875-882

  • Analysis of synergistic muscle activations during locomotion and anatomical tracing of muscle synergy representations in the rodent spinal cord guide the development of a new spinal implant for neuromodulation therapy. In multiple rodent models of spinal cord injury, spatiotemporal stimulation that mimics naturalistic muscle activation patterns promotes improved functional recovery over previously described continuous stimulation protocols.

    • Nikolaus Wenger
    • Eduardo Martin Moraud
    • Grégoire Courtine
    Research
    Nature Medicine
    Volume: 22, P: 138-145

  • Implantable neuroprostheses communicate with the nervous system to provide diagnosis or therapy to the injured body. In this review, we discuss materials-based approaches to overcome the physical and mechanical mismatch at the tissue–implant interface and to design long-term neurointegrated prostheses.

    • Stéphanie P. Lacour
    • Grégoire Courtine
    • Jochen Guck
    Reviews
    Nature Reviews Materials
    Volume: 1, P: 1-14