Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Stephanie Jungmichel Clear advanced filters

  • ADP-ribosylation is a reversible post-translational protein modification involved in many cellular processes. Here the authors describe a sensitive approach for the analysis of ADP-ribosylation sites under physiologic conditions and identify lysine residues as in vivotargets of ADP-ribosylation.

    • Rita Martello
    • Mario Leutert
    • Michael L. Nielsen
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-13

  • DNA double-strand breaks in ribosomal DNA repeats is associated with repression of ribosomal RNA synthesis. Here the authors reveal a cooperation between TOPBP1 and Treacle in the signaling cascade that triggers transcriptional inhibition and nucleolar segregation in response to rDNA breaks.

    • Clémence Mooser
    • Ioanna-Eleni Symeonidou
    • Manuel Stucki
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • Intrinsically disordered proteins can phase separate from the soluble intracellular space. Here the authors show that the nucleic acid-mimicking biopolymer poly(ADP-ribose) (PAR) nucleates intracellular liquid demixing and orchestrates the earliest cellular responses to DNA breakage.

    • Matthias Altmeyer
    • Kai J. Neelsen
    • Jiri Lukas
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-12

  • DNA damage induces silencing of ribosomal RNA (rRNA) transcription. Stucki and colleagues reveal that rRNA silencing is an ATM-dependent pan-nuclear response to irradiation, in which the nucleolar protein Treacle targets DNA-damage protein NBS1 to nucleoli.

    • Dorthe H. Larsen
    • Flurina Hari
    • Manuel Stucki
    Research
    Nature Cell Biology
    Volume: 16, P: 792-803