Nature Search

Increased vegetation growth and carbon stock in China karst via ecological engineering

Since 2000, China has attempted to vegetate huge portions of eroded landscape in its south west, bordering Vietman, Laos, and Myanmar. This study finds that this ecological engineering is combating desertification as vegetation regrows and stores carbon.

Xiaowei Tong
Martin Brandt
Rasmus Fensholt
Research08 Jan 2018
Nature Sustainability

Volume: 1, P: 44-50
The influence of commensal bacteria on infection with enteric viruses

In this Progress article, Stephanie Karst describes how the gut microbiota promotes intestinal infection by enteric viruses. She discusses direct mechanisms by which bacteria stabilize viral particles and facilitate viral attachment to host cells, and indirect mechanisms by which the microbiota suppresses antiviral immune responses.

Stephanie M. Karst
Reviews08 Feb 2016
Nature Reviews Microbiology

Volume: 14, P: 197-204
Plant diversity drives positive microbial associations in the rhizosphere enhancing carbon use efficiency in agricultural soils

The expansion and intensification of agriculture has led to a loss of soil carbon. Here the authors show that increasing plant diversity within an agricultural soil increases positive associations within the soil microbial community, which increases carbon use efficiency.

Luiz A. Domeignoz-Horta
Seraina L. Cappelli
Anna-Liisa Laine
ResearchOpen Access14 Sept 2024
Nature Communications

Volume: 15, P: 1-13
miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

The majority of high grade serous ovarian cancers originate from fallopian tube secretory epithelial cells (FTSECs). Here the authors show that miR-181a drives oncogenic transformation in FTSECs through the cooperative inhibition of the tumor suppressor RB1 and of STING, resulting in genomic instability and suppression of intrinsic interferon signaling.

Matthew Knarr
Rita A. Avelar
Analisa DiFeo
ResearchOpen Access26 Jun 2020
Nature Communications

Volume: 11, P: 1-21
Age-associated features of norovirus infection analysed in mice

Comparing norovirus infection in neonate and adult mice suggests age-dependent differences in passive viral uptake, cellular tropism, interferon regulation and viral dissemination.

Elizabeth A. Kennedy
Somya Aggarwal
Megan T. Baldridge
Research15 May 2023
Nature Microbiology

Volume: 8, P: 1095-1107
Human norovirus culture in B cells

Human noroviruses are a leading cause of foodborne disease. Here the authors facilitate the study of these viruses with protocols for culturing them in human B cells and assessing bacterial stimulation of B cell infection and viral attachment to B cells.

Melissa K Jones
Katrina R Grau
Stephanie M Karst
Protocols29 Oct 2015
Nature Protocols

Volume: 10, P: 1939-1947
Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice

Here the authors show that a murine norovirus causes self-resolving diarrhea in the absence of systemic disease in wild-type neonatal mice and show that lymphocytes affect disease in a dual manner. The data suggests that neonatal mice are a promising model for further studies.

Alexa N. Roth
Emily W. Helm
Stephanie M. Karst
ResearchOpen Access11 Jun 2020
Nature Communications

Volume: 11, P: 1-8
Forest management in southern China generates short term extensive carbon sequestration

Forest management may play an important role in climate change mitigation. Here, Tong et al. combine remote sensing and machine learning modelling to map forest cover dynamics in southern China during 2002–2017, showing effects on carbon sequestration that are extensive but of uncertain longevity and possible negative impact on soil water.

Xiaowei Tong
Martin Brandt
Rasmus Fensholt
ResearchOpen Access08 Jan 2020
Nature Communications

Volume: 11, P: 1-10
Microplastics and nanoplastics barely enhance contaminant mobility in agricultural soils

The transfer of organic contaminants from surface to deeper layers in farmland soils is barely enhanced by microplastic and nanoplastic transport, according to an analytical modeling study.

Stephanie Castan
Charlotte Henkel
Thilo Hofmann
ResearchOpen Access16 Sept 2021
Communications Earth & Environment

Volume: 2, P: 1-9
The intestinal regionalization of acute norovirus infection is regulated by the microbiota via bile acid-mediated priming of type III interferon

The gut microbiota enhances murine norovirus infection in distal regions of the gut, but inhibits viral infection in the proximal small intestine via altered bile acid metabolism and consequent type III interferon production.

Katrina R. Grau
Shu Zhu
Stephanie M. Karst
Research25 Nov 2019
Nature Microbiology

Volume: 5, P: 84-92
The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue

The cell tropism of noroviruses in vivo remains unclear. Here, the dominant cellular targets during acute norovirus infection of immunocompetent mice are shown to be macrophages, dendritic cells, B cells and T cells in the GALT gut-associated lymphoid tissue.

Katrina R. Grau
Alexa N. Roth
Stephanie M. Karst
Research06 Nov 2017
Nature Microbiology

Volume: 2, P: 1586-1591
C mobilisation in disturbed tropical peat swamps: old DOC can fuel the fluvial efflux of old carbon dioxide, but site recovery can occur

Susan Waldron
Leena Vihermaa
Andrew C. G. Henderson
ResearchOpen Access07 Aug 2019
Scientific Reports

Volume: 9, P: 1-12
Environmental DNA reveals arboreal cityscapes at the Ancient Maya Center of Tikal

David L. Lentz
Trinity L. Hamilton
Alison A. Weiss
ResearchOpen Access16 Jun 2021
Scientific Reports

Volume: 11, P: 1-10
Infection of neonatal mice with the murine norovirus strain WU23 is a robust model to study norovirus pathogenesis

A mouse model to study norovirus pathogenesis is described. The murine norovirus strain WU23, originally isolated from an intestinal site, induces severe but self-resolving diarrhea in neonates, reflecting the pathology observed during human norovirus infection.

Amy M. Peiper
Emily W. Helm
Stephanie M. Karst
ResearchOpen Access04 May 2023
Lab Animal

Volume: 52, P: 119-129

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