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A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection

A short isoform of the SARS-CoV-2 host receptor ACE2, expressed in human nasal and bronchial respiratory epithelia, is upregulated in response to interferon treatment and rhinovirus infection, but not SARS-CoV-2 infection.

Cornelia Blume
Claire L. Jackson
Vito Mennella
Research11 Jan 2021
Nature Genetics

Volume: 53, P: 205-214

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A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection

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