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Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway

H3K36 methylation by Set2 targets Rpd3S histone deacetylase to transcribed mRNA genes, repressing internal cryptic promoters and modulating elongation. Here, the authors provide evidence that the Set2-Rpd3S pathway also regulates dynamic expression of mRNAs and lncRNAs.

Ji Hyun Kim
Bo Bae Lee
TaeSoo Kim
ResearchOpen Access28 Nov 2016
Nature Communications

Volume: 7, P: 1-11
Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIV_AD8-EO infection

In this work, the authors study the immunological and virological effects of administering either wild-type anti-HIV-1 broadly neutralizing antibodies (bNAbs) or bNAbs with a mutation that increases binding to Fc-gamma receptors (FcγRs) to rhesus macaques in the acute phase of SHIV_AD8-EO infection.

Joana Dias
Giulia Fabozzi
Richard A. Koup
ResearchOpen Access29 Aug 2024
Nature Communications

Volume: 15, P: 1-18
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Resistance to first line treatment is a major hurdle in cancer treatment, that can be overcome with drug combinations. Here, the authors provide a large drug combination screen across cancer cell lines to benchmark crowdsourced methods and to computationally predict drug synergies.

Michael P. Menden
Dennis Wang
Julio Saez-Rodriguez
ResearchOpen Access17 Jun 2019
Nature Communications

Volume: 10, P: 1-17
Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry

Pratip K Chattopadhyay
David A Price
Mario Roederer
Research23 Jul 2006
Nature Medicine

Volume: 12, P: 972-977
Seventeen-colour flow cytometry: unravelling the immune system

Stephen P. Perfetto
Pratip K. Chattopadhyay
Mario Roederer
Reviews01 Aug 2004
Nature Reviews Immunology

Volume: 4, P: 648-655
Quality assurance for polychromatic flow cytometry

Stephen P Perfetto
David Ambrozak
Mario Roederer
Protocols09 Nov 2006
Nature Protocols

Volume: 1, P: 1522-1530
Quality assurance for polychromatic flow cytometry using a suite of calibration beads

Stephen P Perfetto
David Ambrozak
Mario Roederer
Protocols08 Nov 2012
Nature Protocols

Volume: 7, P: 2067-2079

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Modulation of mRNA and lncRNA expression dynamics by the Set2–Rpd3S pathway

Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIVAD8-EO infection

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Quantum dot semiconductor nanocrystals for immunophenotyping by polychromatic flow cytometry

Seventeen-colour flow cytometry: unravelling the immune system

Quality assurance for polychromatic flow cytometry

Quality assurance for polychromatic flow cytometry using a suite of calibration beads

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Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIV_AD8-EO infection