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Showing 1–1 of 1 results
Advanced filters: Author: Steven P Janasik Clear advanced filters
  • Neurofibromatosis type 1 (NF1) is associated with social dysfunction in children. Here the authors show that Nf1 heterozygous mice have deficits in social memory associated with alterations in amygdala plasticity and Map kinase signaling. Global deletion or amygdala-specific pharmacological inhibition of Pak1 rescued social deficits in Nf1 heterozygous mice.

    • Andrei I Molosh
    • Philip L Johnson
    • Anantha Shekhar
    Research
    Nature Neuroscience
    Volume: 17, P: 1583-1590