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Showing 1–4 of 4 results
Advanced filters: Author: Stuart M Cahalan Clear advanced filters

  • A selective, short-acting agonist for the sphingosine-1-phosphate receptor S1P1 and GFP-S1P1 knock-in mouse model are used to show that both receptor degradation and receptor reserve underlie the mechanisms of lymphocyte sequestration by agonists.

    • Stuart M Cahalan
    • Pedro J Gonzalez-Cabrera
    • Hugh Rosen
    Research
    Nature Chemical Biology
    Volume: 7, P: 254-256

  • Dehydrated hereditary stomatocytosis is a genetic condition in which the permeability of red blood cells to cations in increased. Albuisson and colleagues find that mutations in the mechanically-activated PIEZO1 ion channel are the major cause of the disease and result in more slowly inactivating currents.

    • Juliette Albuisson
    • Swetha E Murthy
    • Ardem Patapoutian
    Research
    Nature Communications
    Volume: 4, P: 1-9

  • This article aims to make the methodology behind the recent spate of papers reportingin situimmune-cell imaging more accessible to the reader and to highlight potential artefacts so that the reader can analyse the data more critically.

    • Ronald N. Germain
    • Mark J. Miller
    • Michel C. Nussenzweig
    Reviews
    Nature Reviews Immunology
    Volume: 6, P: 497-507