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Integrative analysis of genomic and transcriptomic characteristics associated with progression of aggressive thyroid cancer

Anaplastic thyroid cancer (ATC) and advanced differentiated thyroid cancers (DTCs) come with a dismal prognosis. Here, Yoo and colleagues reveal the genomic and transcriptomic landscape of ATC and DTC, highlighting potential therapeutic vulnerabilities.

Seong-Keun Yoo
Young Shin Song
Jeong-Sun Seo
ResearchOpen Access24 Jun 2019
Nature Communications

Volume: 10, P: 1-12
Time-course analysis of DNA damage response-related genes after in vitro radiation in H460 and H1229 lung cancer cell lines

Kang Ho Kim
Hae Yong Yoo
Do-Hyun Nam
ResearchOpen Access02 Jun 2011
Experimental & Molecular Medicine

Volume: 43, P: 419-426
Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells

Hyun-Ock Pae
Gil-Saeng Jeong
Hun-Taeg Chung
ResearchOpen Access01 Jun 2007
Experimental & Molecular Medicine

Volume: 39, P: 267-277
Utilization potential of intraluminal optical coherence tomography for the Eustachian tube

Hayoung Byun
Yeon Hoon Kim
Jae Ho Chung
ResearchOpen Access18 Mar 2021
Scientific Reports

Volume: 11, P: 1-9
In vivo genome editing using the Cpf1 ortholog derived from Eubacterium eligens

Woo-Chan Ahn
Kwang-Hyun Park
Eui-Jeon Woo
ResearchOpen Access26 Sept 2019
Scientific Reports

Volume: 9, P: 1-7
Distal hereditary motor neuropathy in Korean patients with a small heat shock protein 27 mutation

Ki Wha Chung
Sang-Beom Kim
Byung-Ok Choi
ResearchOpen Access20 Jun 2008
Experimental & Molecular Medicine

Volume: 40, P: 304-312
Genome-wide association and expression quantitative trait loci studies identify multiple susceptibility loci for thyroid cancer

Thyroid cancer is the most common cancer in Korea but previous genome-wide association studies on risk loci have been conducted only in Europeans. Here the authors identify three previously reported loci and seven putatively new loci in the Korean population.

Ho-Young Son
Yul Hwangbo
Jong-Il Kim
ResearchOpen Access13 Jul 2017
Nature Communications

Volume: 8, P: 1-12
Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis

The non-structural protein NSs of the severe fever with thrombocytopenia syndrome virus interacts with ABIN2 and promotes formation and signalling of the TPL2–ABIN2–p105 kinase complex to induce expression of the immune-suppressive cytokine IL-10 and enhance viral pathogenesis.

Younho Choi
Su-Jin Park
Jae U. Jung
Research07 Jan 2019
Nature Microbiology

Volume: 4, P: 429-437
Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis

Cheol-Jung Lee
Su-Jin Moon
Yong-Yeon Cho
ResearchOpen Access14 Mar 2018
Cell Death & Disease

Volume: 9, P: 1-21
Depression, performance status, and discontinued treatment mediate an association of curability belief with prognosis in advanced cancer patients

Je-Yeon Yun
Ju Youn Jung
Young Ho Yun
ResearchOpen Access24 Nov 2024
Scientific Reports

Volume: 14, P: 1-12
Characteristics of recent HIV infection among individuals newly diagnosed as HIV-positive in South Korea (2008–2015)

Myeongsu Yoo
Jin-Sook Wang
Mee-Kyung Kee
ResearchOpen Access22 Jun 2022
Scientific Reports

Volume: 12, P: 1-11
ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation

Dong Im Cho
Min Joo Ahn
Youngkeun Ahn
ResearchOpen Access13 Feb 2023
Experimental & Molecular Medicine

Volume: 55, P: 426-442
The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis

Hak Su Kim
Su-Jin Moon
Jin Woo Song
ResearchOpen Access14 May 2021
Experimental & Molecular Medicine

Volume: 53, P: 864-874
Suppression of PPARγ-mediated monoacylglycerol O-acyltransferase 1 expression ameliorates alcoholic hepatic steatosis

Jung Hwan Yu
Su Jin Song
Jae-woo Kim
ResearchOpen Access11 Jul 2016
Scientific Reports

Volume: 6, P: 1-12
NADPH oxidase 4 is required for the generation of macrophage migration inhibitory factor and host defense against Toxoplasma gondii infection

Ji Hye Kim
Jina Lee
Jae-Min Yuk
ResearchOpen Access25 Jul 2017
Scientific Reports

Volume: 7, P: 1-13
Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes

Se-Jin Kim
Joon Ho Hur
Raekil Park
ResearchOpen Access20 Feb 2015
Experimental & Molecular Medicine

Volume: 47, P: e142

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Integrative analysis of genomic and transcriptomic characteristics associated with progression of aggressive thyroid cancer

Time-course analysis of DNA damage response-related genes after in vitro radiation in H460 and H1229 lung cancer cell lines

Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells

Utilization potential of intraluminal optical coherence tomography for the Eustachian tube

In vivo genome editing using the Cpf1 ortholog derived from Eubacterium eligens

Distal hereditary motor neuropathy in Korean patients with a small heat shock protein 27 mutation

Genome-wide association and expression quantitative trait loci studies identify multiple susceptibility loci for thyroid cancer

Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis

Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis

Depression, performance status, and discontinued treatment mediate an association of curability belief with prognosis in advanced cancer patients

Characteristics of recent HIV infection among individuals newly diagnosed as HIV-positive in South Korea (2008–2015)

ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation

The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis

Suppression of PPARγ-mediated monoacylglycerol O-acyltransferase 1 expression ameliorates alcoholic hepatic steatosis

NADPH oxidase 4 is required for the generation of macrophage migration inhibitory factor and host defense against Toxoplasma gondii infection

Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes

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