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Showing 1–12 of 12 results

Advanced filters: Author: Sujata Rao Clear advanced filters

A generative AI-discovered TNIK inhibitor for idiopathic pulmonary fibrosis: a randomized phase 2a trial

Preliminary results from a phase 2a trial involving 71 patients suggest that a new agent, discovered and designed with artificial intelligence assistance, is safe and effective for the treatment of idiopathic pulmonary fibrosis.

Zuojun Xu
Feng Ren
Alex Zhavoronkov
ResearchOpen Access03 Jun 2025
Nature Medicine

Volume: 31, P: 2602-2610
A direct and melanopsin-dependent fetal light response regulates mouse eye development

During retinal vascular development there is simultaneous regression of the hyaloid vasculature and formation of the retinal vasculature; here it is demonstrated that regression of developing vasculature is light dependent and acts via the photoreceptor melanopsin.

Sujata Rao
Christina Chun
Richard A. Lang
Research16 Jan 2013
Nature

Volume: 494, P: 243-246
WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

Ivan B. Lobov
Sujata Rao
Richard A. Lang
Research15 Sept 2005
Nature

Volume: 437, P: 417-421
Regulation of angiogenesis by a non-canonical Wnt–Flt1 pathway in myeloid cells

James A. Stefater III
Ian Lewkowich
Richard A. Lang
Research29 May 2011
Nature

Volume: 474, P: 511-515
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models

An AI-generated small-molecule inhibitor treats fibrosis in vivo and in phase I clinical trials.

Feng Ren
Alex Aliper
Alex Zhavoronkov
ResearchOpen Access08 Mar 2024
Nature Biotechnology

Volume: 43, P: 63-75
An opsin 5–dopamine pathway mediates light-dependent vascular development in the eye

Nguyen et al. show that neuropsin (OPN5) suppresses hyaloid vessel regression in the developing mouse retina in response to light, by regulation of the dopamine reuptake transporter and DRD2-dependent suppression of VEGFR2 activity.

Minh-Thanh T. Nguyen
Shruti Vemaraju
Richard A. Lang
Research01 Apr 2019
Nature Cell Biology

Volume: 21, P: 420-429
DIABETIC SERUM INDUCES APOPTOSIS AND THE EXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN PC-12 CELLS. 563

Jayshree K Rao
Sujata Gandhi
Mark J.S Miller
Research01 Apr 1996
Pediatric Research

Volume: 39, P: 96
A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations

Pavithra Nagarajan
Thomas W. Winkler
Heming Wang
Research04 Apr 2025
Molecular Psychiatry

Volume: 30, P: 3660-3672
Diabetic retinopathy screening in rural India with portable fundus camera and artificial intelligence using eye mitra opticians from Essilor India

Alok Bahl
Sujata Rao
Correspondence15 Dec 2020
Eye

Volume: 36, P: 230-231
Neuronal Bmal1 regulates retinal angiogenesis and neovascularization in mice

Silencing of the retinal clock through targeting neuronal Bmal1 could constitute an approach to treating some forms of retinopathy.

Vijay K. Jidigam
Onkar B. Sawant
Sujata Rao
ResearchOpen Access06 Aug 2022
Communications Biology

Volume: 5, P: 1-11
A non-invasive method for concurrent detection of early-stage women-specific cancers

Ankur Gupta
Ganga Sagar
Rajat Anand
ResearchOpen Access10 Feb 2022
Scientific Reports

Volume: 12, P: 1-12
Compartmentalized gene expression profiling of receptive endometrium reveals progesterone regulated ENPP3 is differentially expressed and secreted in glycosylated form

Nageswara Rao Boggavarapu
Sujata Lalitkumar
Kristina Gemzell-Danielsson
ResearchOpen Access26 Sept 2016
Scientific Reports

Volume: 6, P: 1-13