The bacterium Pseudomonas aeruginosa has three type-VI secretion systems that exhibit differences in the size and domain organization of one of their components, protein TssA. Here, Fecht et al. provide insights into the functions of the different TssA domains and propose a model for the role played by TssA proteins in secretion-system assembly.
- Selina Fecht
- Patricia Paracuellos
- Alain Filloux
