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Showing 1–4 of 4 results
Advanced filters: Author: Sukjun Kim Clear advanced filters

  • miRNAs are loaded into Argonaute protein and repress complementary mRNA targets. Here the authors show the unappreciated role of RNA binding proteins for efficient miRNA targeting and expand the current understanding of miRNA targeting.

    • Sukjun Kim
    • Soyoung Kim
    • Daehyun Baek
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Here, Kim et al. apply various sequencing techniques (RPF-seq, QTI-seq, mRNA-seq, sRNA-seq) to unravel the high-resolution, longitudinal translatome and transcriptome of SARS-CoV-2. They identify a translation initiation site in the leader sequence of all genomic and subgenomic RNAs and show its relevance for the SARS-CoV-2 translatome.

    • Doyeon Kim
    • Sukjun Kim
    • Daehyun Baek
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • Daehyun Baek and colleagues present a systematic analysis of more than 2 billion potential miRNA–gene target interactions using publicly available human microarray data. The authors find evidence for four canonical and seven non-canonical site types that show detectable downregulation of target genes, and they present functional validation for the new site types.

    • Doyeon Kim
    • You Me Sung
    • Daehyun Baek
    Research
    Nature Genetics
    Volume: 48, P: 1517-1526