Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Sung-Ik Cho Clear advanced filters

  • Base editing in nuclear DNA and mitochondrial DNA (mtDNA) is broadly useful for biomedical research, medicine, and biotechnology. Here the authors present zinc finger deaminases which catalyze targeted C-to-T base conversions without inducing unwanted indels in human cells.

    • Kayeong Lim
    • Sung-Ik Cho
    • Jin-Soo Kim
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • Plant-optimized transcription activator-like effector-linked deaminases enable site-specific A-to-G base editing in the chloroplast genome, leading to heritable homoplasmic base conversions and phenotypic changes.

    • Young Geun Mok
    • Sunghyun Hong
    • Jin-Soo Kim
    ResearchOpen Access
    Nature Plants
    Volume: 8, P: 1378-1384

  • Cas9 nickases (nCas9s) produce nicks or single-strand breaks in the DNA. Here the authors analyse the on- and off-target nicks generated by these nickases, and show that nCas9 (H840A) but not nCas9 (D10A) can cleave both strands and produce unwanted DNA double-strand breaks.

    • Jaesuk Lee
    • Kayeong Lim
    • Jin-Soo Kim
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11

  • Monomeric DdCBEs (mDdCBEs), enabling mitochondrial DNA editing with high efficiencies of up to 50%, when transiently expressed in cultured human cells and nearly homoplasmic C-to-T editing via AAV.

    • Young Geun Mok
    • Ji Min Lee
    • Jin-Soo Kim
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10