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Showing 1–2 of 2 results
Advanced filters: Author: Sung-Ji Ahn Clear advanced filters
  • Rodent stroke models are crucial but often invasive and limited in translational relevance. Here, the authors show that magnetic particle delivery creates a reproducible, minimally invasive thrombotic stroke model in awake mice, improving translational potential.

    • Kimberly Marks
    • Sung-Ji Ahn
    • Josef Anrather
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16
  • This study examines the contribution of a specific phosphatidylinositol 3-kinase (PI3K) isoform, namely PI3Kγ, to hippocampal synaptic plasticity and behavior. The authors find that the loss of PI3Kγ can specifically impair NMDA receptor–mediated long-term depression and cognitive functions that rely on behavioral flexibility.

    • Jae-Ick Kim
    • Hye-Ryeon Lee
    • Bong-Kiun Kaang
    Research
    Nature Neuroscience
    Volume: 14, P: 1447-1454