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Showing 1–11 of 11 results
Advanced filters: Author: Sung-hoon Back Clear advanced filters

  • Flexible strain-gauge sensors, which could eventually be used in electronic skin, generally require complex device architectures. A simple and highly sensitive resistive sensor for the detection of pressure, shear and torsion with discernible strain-gauge factors has now been fabricated using two interlocked arrays of platinum-coated polymer nanofibres.

    • Changhyun Pang
    • Gil-Yong Lee
    • Kahp-Yang Suh
    Research
    Nature Materials
    Volume: 11, P: 795-801

  • How clamp conformation is regulated in the transcription cycle of stalk-containing archaeal and eukaryotic RNA polymerase (RNAP) systems is still not well understood. Here, the authors combine cryo-EM, X-ray crystallography and photo-crosslinking assays to structurally characterise RNAP, the RNAP-TFEα binary and RNAP-TFEα-promoter DNA ternary complexes from the archaea Thermococcus kodakarensis and enables them to describe the dynamic conformational changes of the general transcription factor TFEα and RNAP during the early stage of transcription cycle.

    • Sung-Hoon Jun
    • Jaekyung Hyun
    • Katsuhiko S. Murakami
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Carbon nanotube–polymer composites containing secondary fillers are thought to possess enhanced electrical and mechanical properties. Here the authors combine Monte Carlo calculations with resistivity experiments to study the effect of filler size and shape on electrical conductivity.

    • Sung-Hoon Park
    • Jinyoung Hwang
    • Sang Hyun Lee
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11

  • In the presence of stress stimuli, the endoplasmic reticulum either adapts the protein synthesis or triggers an apoptotic response, but the mechanisms underlying this decision are unknown. Kaufman and colleagues show that the ER stress response factors ATF4 and CHOP increase protein synthesis, which in turn induces oxidative stress and increased ATP consumption, leading to cell death during chronic ER stress.

    • Jaeseok Han
    • Sung Hoon Back
    • Randal J. Kaufman
    Research
    Nature Cell Biology
    Volume: 15, P: 481-490

  • The type III secretion system effectors NleB and SseK are glycosyltransferases (GT) that specifically glycosylate arginine residues. Here the authors provide insights into their mechanism by combining X-ray crystallography, NMR, enzyme kinetics measurements, molecular dynamics simulations and in vivo experiments and show that SseK/NleB enzymes are retaining GTs.

    • Jun Bae Park
    • Young Hun Kim
    • Hyun-Soo Cho
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15

  • We suggest synaptic devices using cation migration along thickness direction in a new class of 2D layered materials. An electrochemically active metal, such as Ag and Cu, is used for the operation of the synaptic device and chromium thiophosphate (CrPS4) single crystal is used as an electrolyte material. Multi-stable resistive states, short-term plasticity, and long-term potentiation are observed by controlling external voltage pulse with height smaller than 0.3 V. Given that simple mechanical exfoliation can generate very thin CrPS4 layers, the vertical Ag/CrPS4/Au capacitor offers a promising inorganic synaptic device compatible with next-generation flexible neuromorphic technology.

    • Mi Jung Lee
    • Sangik Lee
    • Bae Ho Park
    ResearchOpen Access
    NPG Asia Materials
    Volume: 10, P: 23-30

  • Defects in mitochondrial function have been believed to contribute to insulin resistance. Myung-Shik Lee and colleagues now show that mitochondrial dysfunction in muscle induced by tissue-specific deficiency of autophagy results in upregulation of Fgf21 and improved metabolism, suggesting that at least some mitochondrial dysfunction may actually be beneficial.

    • Kook Hwan Kim
    • Yeon Taek Jeong
    • Myung-Shik Lee
    Research
    Nature Medicine
    Volume: 19, P: 83-92