Nature Search

Cathepsin L as a dual-target to mitigate muscle wasting while enhancing anti-tumor efficacy of anti-PD-L1

Immune checkpoint inhibitors (ICIs) are associated with side effects such as muscle wasting. Here, the authors discover that targeting cathepsin L not only suppresses ICI-induced CD8 + T cell-mediated muscle wasting but also enhances ICI anti-tumor efficacy.

Se-Young Park
Kyuwon Son
Na-Young Song
ResearchOpen Access28 Nov 2025
Nature Communications

Volume: 16, P: 1-19
One-ninth magnetization plateau stabilized by spin entanglement in a kagome antiferromagnet

Magnets with frustrated interactions are predicted to form quantum entangled states that feature measurable plateaus in their magnetization. Evidence for one of these plateau phases has now been found in a kagome lattice antiferromagnet.

Sungmin Jeon
Dirk Wulferding
Kwang-Yong Choi
Research12 Jan 2024
Nature Physics

Volume: 20, P: 435-441
Emergence of flat bands and ferromagnetic fluctuations via orbital-selective electron correlations in Mn-based kagome metal

Kagome materials host nearly dispersionless electronic bands, but an ideal flat band close to the Fermi level is difficult to realize. Here the authors report evidence for a flat band near the Fermi level and flat-band-originated ferromagnetic fluctuation induced by orbital selective correlations in Sc₃Mn₃Al₇Si₅.

Subhasis Samanta
Hwiwoo Park
Heung-Sik Kim
ResearchOpen Access25 Jun 2024
Nature Communications

Volume: 15, P: 1-11
Discovery of a peripheral 5HT_2A antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitis

Metabolic Dysfunction-Associated Steatohepatitis (MASH), an advanced form of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), can progress to liver fibrosis. Here, the authors develop a peripheral 5HT_2A antagonist for the treatment of MASLD and MASH.

Haushabhau S. Pagire
Suvarna H. Pagire
Jin Hee Ahn
ResearchOpen Access20 Jan 2024
Nature Communications

Volume: 15, P: 1-12
Mapping the spectrum of 3D communities in human chromosome conformation capture data

Sang Hoon Lee
Yeonghoon Kim
Ludvig Lizana
ResearchOpen Access02 May 2019
Scientific Reports

Volume: 9, P: 1-7
Suppression of magnetic ordering in XXZ-type antiferromagnetic monolayer NiPS₃

Exploring the ground state of two-dimensional (2D) magnetic systems enriches the fundamental understanding of magnetism and boosts the applications. The authors here show the suppression of magnetic order and 2D XY behavior in XXZ-type antiferromagnet NiPS₃ when approaching the monolayer limit by Raman spectroscopy.

Kangwon Kim
Soo Yeon Lim
Hyeonsik Cheong
ResearchOpen Access21 Jan 2019
Nature Communications

Volume: 10, P: 1-9
AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10

Ho-June Lee
Jong-Ok Pyo
Yong-Keun Jung
Research21 Oct 2007
Nature Cell Biology

Volume: 9, P: 1303-1310
Downregulation of CR6-interacting factor 1 suppresses keloid fibroblast growth via the TGF-β/Smad signaling pathway

Harsha Nagar
Sungmin Kim
Cuk-Seong Kim
ResearchOpen Access12 Jan 2021
Scientific Reports

Volume: 11, P: 1-13
Decreased FBP1 expression rewires metabolic processes affecting aggressiveness of glioblastoma

Beomseok Son
Sungmin Lee
BuHyun Youn
Research23 Aug 2019
Oncogene

Volume: 39, P: 36-49
In vitro larvicidal efficacy of Lantana camara essential oil and its nanoemulsion and enzyme inhibition kinetics against Anopheles culicifacies

Shruti Sonter
Manish Kumar Dwivedi
Prashant Kumar Singh
ResearchOpen Access15 Jul 2024
Scientific Reports

Volume: 14, P: 1-17
Visit-to-visit blood pressure variability and mortality and cardiovascular outcomes after acute myocardial infarction

Eun Ho Choo
Ji-Su Mok
Kiyuk Chang
Research13 Sept 2021
Journal of Human Hypertension

Volume: 36, P: 960-967

Search

Cathepsin L as a dual-target to mitigate muscle wasting while enhancing anti-tumor efficacy of anti-PD-L1

One-ninth magnetization plateau stabilized by spin entanglement in a kagome antiferromagnet

Emergence of flat bands and ferromagnetic fluctuations via orbital-selective electron correlations in Mn-based kagome metal

Discovery of a peripheral 5HT_2A antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitis

Mapping the spectrum of 3D communities in human chromosome conformation capture data

Suppression of magnetic ordering in XXZ-type antiferromagnetic monolayer NiPS₃

AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10

Downregulation of CR6-interacting factor 1 suppresses keloid fibroblast growth via the TGF-β/Smad signaling pathway

Decreased FBP1 expression rewires metabolic processes affecting aggressiveness of glioblastoma

In vitro larvicidal efficacy of Lantana camara essential oil and its nanoemulsion and enzyme inhibition kinetics against Anopheles culicifacies

Visit-to-visit blood pressure variability and mortality and cardiovascular outcomes after acute myocardial infarction

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