The chromatin-associated protein HP1α is known to also be involved in kinetochore assembly and sister chromatid cohesion. Chakraborty et al.show that phosphorylation at the hinge region of HP1α is required for the onset of mitosis, and facilitates Sgo1 binding to mitotic centromeres.
- Arindam Chakraborty
- Kannanganattu V. Prasanth
- Supriya G. Prasanth