Genome-wide analysis of the chromatin modification patterns at Pol III genes showed a correlation between histone modifications and tissue specific transcription of Pol III genes. Surprisingly, it was also discovered that Pol II and its associated basal factors are recruited to expressed Pol III transcribed genes. One idea is that Pol II could help keep chromatin around Pol III genes in an open state.
- Artem Barski
- Iouri Chepelev
- Keji Zhao
