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Showing 1–9 of 9 results

Advanced filters: Author: Surya A Reis Clear advanced filters

Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16
Light-controlled modulation of gene expression by chemical optoepigenetic probes

An approach called chemo-optical modulation of epigenetically regulated transcription (COMET) combines azobenzene-based photochromic HDAC inhibitors with microprocessor-controlled LED plates to regulate gene expression profiles in a light-dependent manner.

Surya A Reis
Balaram Ghosh
Ralph Mazitschek
Research14 Mar 2016
Nature Chemical Biology

Volume: 12, P: 317-323
Automated real-world data integration improves cancer outcome prediction

A study generates a clinicogenomics dataset resource, MSK-CHORD, that combines natural language processing-derived clinical annotations with patient medical data from various sources to improve models of cancer outcome.

Justin Jee
Christopher Fong
Xinran Bi
ResearchOpen Access06 Nov 2024
Nature

Volume: 636, P: 728-736
Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability

The activity-regulated cytoskeleton-associated protein (Arc) has been implicated in synaptic plasticity and memory consolidation. Here the authors show that Arc acetylation regulates its stability and identify small molecules that modulate Arc expression.

Jasmin Lalonde
Surya A. Reis
Stephen J. Haggarty
ResearchOpen Access21 Nov 2017
Nature Communications

Volume: 8, P: 1-17
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia

Zachary C. Rosenthal
Daniel M. Fass
Stephen J. Haggarty
ResearchOpen Access20 Apr 2024
Scientific Reports

Volume: 14, P: 1-29
High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy

Chialin Cheng
Surya A. Reis
Stephen J. Haggarty
ResearchOpen Access23 Aug 2021
Scientific Reports

Volume: 11, P: 1-21
Disruption of the psychiatric risk gene Ankyrin 3 enhances microtubule dynamics through GSK3/CRMP2 signaling

Jacob C. Garza
Xiaoli Qi
Tracey L. Petryshen
ResearchOpen Access25 Jul 2018
Translational Psychiatry

Volume: 8, P: 1-14
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22