Nature Search

Higher mortality following SARS-CoV-2 infection in rural versus urban dwellers persists for two years post-infection

People living in rural areas of the United States have poorer outcomes from acute COVID-19. Here, the authors show that higher mortality rates among rural dwellers persist for up to two years after the initial infection, even after accounting for baseline risk factors.

A. Jerrod Anzalone
Michael T. Vest
Christopher G. Chute
ResearchOpen Access08 Oct 2025
Nature Communications

Volume: 16, P: 1-18
Proximity ferroelectricity in wurtzite heterostructures

Proximity ferroelectricity is reported in wurtzite heterostructures, which enables polarization reversal in wurtzites without the chemical or structural disorder that accompanies elemental substitution.

Chloe H. Skidmore
R. Jackson Spurling
Jon-Paul Maria
Research08 Jan 2025
Nature

Volume: 637, P: 574-579
AR alterations inform circulating tumor DNA detection in metastatic castration resistant prostate cancer patients

Liquid biopsy assays are important to prognosticate outcomes of metastatic castration-resistant prostate cancer (mCRPC) patients treated with androgen receptor (AR) inhibitors. Here this group reports detecting circulating tumor DNA in limiting plasma cell-free DNA of mCRPC patients as prognostic marker of poor survival after AR treatment.

Todd P. Knutson
Bin Luo
Scott M. Dehm
ResearchOpen Access11 Dec 2024
Nature Communications

Volume: 15, P: 1-15
The Bioavailability of Iron in Different Weaning Foods and the Enhancing Effect of a Fruit Drink Containing Ascorbic Acid

Susan Fairweather-Tait
Tom Fox
John Eagles
Research01 Apr 1995
Pediatric Research

Volume: 37, P: 389-394
Lactoferrin and Iron Absorption in Newborn Infants

Susan J Fairweather-Tait
Susan E Balmer
Margaret J Minski
Research01 Dec 1987
Pediatric Research

Volume: 22, P: 651-654
Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

The authors describe a neurogenic niche in the postnatal hypothalamus of mice wherein β2-tanycytes generate neurons in response to high-fat diet. Blocking this neurogenesis leads to attenuated weight gain and increased activity levels.

Daniel A Lee
Joseph L Bedont
Seth Blackshaw
Research25 Mar 2012
Nature Neuroscience

Volume: 15, P: 700-702
CaMKII oxidation is a critical performance/disease trade-off acquired at the dawn of vertebrate evolution

Natural selection may favor traits underlying aging-related diseases if they benefit the young. Wang et al. find that oxidative activation of CaMKII provides physiological benefits critical to the initial and continued success of vertebrates but at the cost of disease, frailty, and shortened lifespan.

Qinchuan Wang
Erick O. Hernández-Ochoa
Mark E. Anderson
ResearchOpen Access26 May 2021
Nature Communications

Volume: 12, P: 1-17
A phase 2 trial of avelumab in men with aggressive-variant or neuroendocrine prostate cancer

Landon C. Brown
Susan Halabi
Andrew J. Armstrong
Research15 Mar 2022
Prostate Cancer and Prostatic Diseases

Volume: 25, P: 762-769
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

Huntington's disease is a neurodegenerative disease caused by the accumulation of mutant htt protein. Now, two groups led by Dimitri Krainc and Wenzhen Duan report that mutant htt binds and inactivates the deacetylase enzyme SIRT1 and that SIRT1 overexpression is protective in Huntington's disease mouse models.

Mali Jiang
Jiawei Wang
Wenzhen Duan
Research18 Dec 2011
Nature Medicine

Volume: 18, P: 153-158
Updated 5-year results for short course abiraterone acetate and LHRH agonist for unfavorable intermediate and favorable high-risk prostate cancer

Ryan E. Fecteau
Bridget F. Koontz
Andrew J. Armstrong
Research22 Feb 2024
Prostate Cancer and Prostatic Diseases

Volume: 28, P: 503-505
Prognostic and predictive analyses of circulating plasma biomarkers in men with metastatic castration resistant prostate cancer treated with docetaxel/prednisone with or without bevacizumab

Andrew B. Nixon
Yingmiao Liu
Susan Halabi
Research12 Feb 2024
Prostate Cancer and Prostatic Diseases

Volume: 28, P: 355-362
DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders

Yan Jouroukhin
Yusuke Kageyama
Mikhail V. Pletnikov
ResearchOpen Access12 Apr 2018
Translational Psychiatry

Volume: 8, P: 1-12
Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI

Usha Nekanti
Pooja S. Sakthivel
Aileen J. Anderson
ResearchOpen Access18 Mar 2024
npj Regenerative Medicine

Volume: 9, P: 1-20
Unsupervised data-driven stratification of mentalizing heterogeneity in autism

Michael V. Lombardo
Meng-Chuan Lai
Simon Baron-Cohen
ResearchOpen Access18 Oct 2016
Scientific Reports

Volume: 6, P: 1-15

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