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Advanced filters: Author: Sylvain Audia Clear advanced filters

  • Myelofibrosis is a chronic degenerative disorder characterized by progressive bone marrow fibrosis. Here, the authors show that the chaperone HSP27 contributes to myelofibrosis via regulation of the JAK2/STAT5 pathway, and that antisense oligonucleotides targeting HSP27 are effective in two mouse models of the disease

    • Margaux Sevin
    • Lucia Kubovcakova
    • Aurélie de Thonel
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13