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Experimental & Molecular Medicine (2)
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Showing 1–5 of 5 results

Advanced filters: Author: Tae-Su Han Clear advanced filters

The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism

Ferroptosis is an iron-dependent cell death mechanism that is emerging as a target for cancer therapy. Here, the authors find that lipoprotein-associated phospholipase A2 modulates ferroptosis resistance by controlling phospholipid metabolism.

Mihee Oh
Seo Young Jang
Eun-Woo Lee
ResearchOpen Access15 Sept 2023
Nature Communications

Volume: 14, P: 1-17
Epigenetic regulation of SMAD3 by histone methyltransferase SMYD2 promotes lung cancer metastasis

Kwangho Kim
Tae Young Ryu
Hyun-Soo Cho
ResearchOpen Access01 May 2023
Experimental & Molecular Medicine

Volume: 55, P: 952-964
Human gut-microbiome-derived propionate coordinates proteasomal degradation via HECTD2 upregulation to target EHMT2 in colorectal cancer

Tae Young Ryu
Kwangho Kim
Hyun-Soo Cho
ResearchOpen Access01 Jan 2022
The ISME Journal

Volume: 16, P: 1205-1221
SMYD family in cancer: epigenetic regulation and molecular mechanisms of cancer proliferation, metastasis, and drug resistance

Tae-Su Han
Dae-Soo Kim
Hyun-Soo Cho
ReviewsOpen Access01 Nov 2024
Experimental & Molecular Medicine

Volume: 56, P: 2325-2336
Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activation

Sang-Hyun Lee
Jin-Man Kim
Jeong-Ki Min
ResearchOpen Access28 Sept 2020
Cell Death & Differentiation

Volume: 28, P: 968-984