A catalytic para-selective alkylation reaction connects C–H functionalization and decarboxylative coupling strategies using simple bases to trap a previously hidden intermediate. This reaction exploits an ‘inverted sequence’ that forms the C–C bond prior to C–H bond cleavage and provides a new entry into C–H functionalization reactions.
- Francisco de Azambuja
- Ming-Hsiu Yang
- Ryan A. Altman
