The sodium–potassium ATPase is an ATP-powered ion pump that creates concentration gradients for sodium and potassium ions across the plasma membrane of animal cells, a process essential, for example, in the action potentials of nerve cells. Here the crystal structure of the sodium–potassium pump in the shark, which is highly homologous to the human pump, is described.
- Takehiro Shinoda
- Haruo Ogawa
- Chikashi Toyoshima