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Showing 1–4 of 4 results

Advanced filters: Author: Tal Givony Clear advanced filters

Thymic mimetic cells function beyond self-tolerance

Multiomic analyses of mouse thymic epithelial cells identify several unconventional subsets that are mimetics of various populations of terminally differentiated parenchymal cells and provide insights into their development, molecular features and function.

Tal Givony
Dena Leshkowitz
Jakub Abramson
Research06 Sept 2023
Nature

Volume: 622, P: 164-172
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease

A large fraction of patients with APS-1 and coeliac disease develop enamel dystrophy, characterized by the presence of autoantibodies against the enamel matrix, which are generated through the breakdown of either central (APS-1) or peripheral (coeliac) tolerance to a battery of ameloblast-sepecific proteins.

Yael Gruper
Anette S. B. Wolff
Jakub Abramson
Research22 Nov 2023
Nature

Volume: 624, P: 653-662
Author Correction: Thymic mimetic cells function beyond self-tolerance

Tal Givony
Dena Leshkowitz
Jakub Abramson
Amendments and Corrections30 Nov 2023
Nature

Volume: 624, P: E4
Extrathymic expression of Aire controls the induction of effective T_H17 cell-mediated immune response to Candida albicans

Abramson and colleagues show that Aire⁺MHCII⁺ ILC3s sense, internalize and present Candida albicans and modulate the induction of C. albicans-specific T_H17 cells.

Jan Dobeš
Osher Ben-Nun
Jakub Abramson
Research27 Jun 2022
Nature Immunology

Volume: 23, P: 1098-1108