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Showing 1–2 of 2 results
Advanced filters: Author: Tatiana Proust Clear advanced filters

  • BRAF inhibitor response in melanoma is variable, and BRAF mutated patients often relapse. Here, the authors show that androgen receptor expression is linked to BRAF inhibitor response, and is a potential therapeutic target to increase efficacy.

    • Anastasia Samarkina
    • Markus Kirolos Youssef
    • Gian Paolo Dotto
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19

  • Reduced glomerular filtration rate (eGFR) is a hallmark of chronic kidney disease. Here, Pattaro et al. conduct a meta-analysis to discover several new loci associated with variation in eGFR and find that genes associated with eGFR loci often encode proteins potentially related to kidney development.

    • Cristian Pattaro
    • Alexander Teumer
    • Caroline S. Fox
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-19