Nature Search

Glacial Nomenclature and Scott's Antarctic Expedition

GRIFFITH TAYLOR
Research26 Oct 1916
Nature

Volume: 98, P: 149-150
Archaeological and molecular evidence for ancient chickens in Central Asia

The origin and dispersal of the chicken across Eurasia is unclear. Here, the authors examine eggshell fragments from southern Central Asia with paleoproteomics to identify chicken eggshells, suggesting that chickens may have been an important dietary component as early as 400BCE.

Carli Peters
Kristine K. Richter
Robert N. Spengler III
ResearchOpen Access02 Apr 2024
Nature Communications

Volume: 15, P: 1-14
Arctic Ocean virus communities and their seasonality, bipolarity, and prokaryotic associations

Based on bulk DNA time-series sequencing of the surface Arctic Ocean, Calayag et al. show that planktonic viruses are strongly seasonal in abundance and community composition, and are correlated strongly with their prokaryote hosts.

Alyzza M. Calayag
Taylor Priest
David M. Needham
ResearchOpen Access11 Jul 2025
Nature Communications

Volume: 16, P: 1-15
Author Correction: Seasonal recurrence and modular assembly of an Arctic pelagic marine microbiome

Taylor Priest
Ellen Oldenburg
Matthias Wietz
Amendments and CorrectionsOpen Access18 Feb 2025
Nature Communications

Volume: 16, P: 1
Seasonal recurrence and modular assembly of an Arctic pelagic marine microbiome

Microbial communities are shaped by their environment. Here, the authors demonstrate temporal structuring of microbial communities in the pelagic Arctic Ocean, using remote, long-term sampling with long-read metagenomics and SSU ribosomal metabarcoding.

Taylor Priest
Ellen Oldenburg
Matthias Wietz
ResearchOpen Access03 Feb 2025
Nature Communications

Volume: 16, P: 1-13
A mutational hotspot that determines highly repeatable evolution can be built and broken by silent genetic changes

Mutational hotspots can determine evolutionary outcomes and make evolution repeatable. Experiments in bacteria reveal that a powerfully deterministic genetic hotspot can be built and broken by a handful of silent mutations, highlighting an underappreciated role for silent genetic variation in determining adaptive outcomes.

James S. Horton
Louise M. Flanagan
Tiffany B. Taylor
ResearchOpen Access19 Oct 2021
Nature Communications

Volume: 12, P: 1-10
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Lung adenocarcinoma promotion by air pollutants

Combination of epidemiology, preclinical models and ultradeep DNA profiling of clinical cohorts unpicks the inflammatory mechanism by which air pollution promotes lung cancer

William Hill
Emilia L. Lim
Charles Swanton
Research05 Apr 2023
Nature

Volume: 616, P: 159-167
Larval fish dispersal in a coral-reef seascape

Larval dispersal of clownfish and butterflyfish across a 10,000 km² area was tracked over 2 years, a large enough scale to inform the design of marine reserve networks and test their performance.

Glenn R. Almany
Serge Planes
Geoffrey P. Jones
Research08 May 2017
Nature Ecology & Evolution

Volume: 1, P: 1-7
Joseph Campbell’s Oriental mythology in Ghost in the Shell (1995) and Occidental mythology in Ghost in the Shell (2017)

Qiao Li
Edwin L. Phil Tan
Jianhua Yang
ResearchOpen Access07 Dec 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-10
Neoantigen-directed immune escape in lung cancer evolution

RNA sequencing data and tumour pathology observations of non-small-cell lung cancers indicate that the immune cell microenvironment exerts strong evolutionary selection pressures that shape the immune-evasion capacity of tumours.

Rachel Rosenthal
Elizabeth Larose Cadieux
Andrew Kidd
Research20 Mar 2019
Nature

Volume: 567, P: 479-485
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution

Analysis of whole-genome doubling (WGD) by using cancer sequencing data combined with simulations of tumor evolution suggests that there is negative selection against homozygous loss of essential genes before WGD but not after.

Saioa López
Emilia L. Lim
Nicholas McGranahan
Research05 Mar 2020
Nature Genetics

Volume: 52, P: 283-293
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx

Analyses of the TRACERx study unveil the relationship between tissue morphology, the underlying evolutionary genomic landscape, and clinical and anatomical relapse risk of lung adenocarcinomas.

Takahiro Karasaki
David A. Moore
Mariam Jamal-Hanjani
Research12 Apr 2023
Nature Medicine

Volume: 29, P: 833-845
Body composition and lung cancer-associated cachexia in TRACERx

Results of the TRACERx study shed new light into the association between body composition and body weight with survival in individuals with non-small cell lung cancer, and delineate potential biological processes and mediators contributing to the development of cancer-associated cachexia.

Othman Al-Sawaf
Jakob Weiss
Charles Swanton
Research12 Apr 2023
Nature Medicine

Volume: 29, P: 846-858
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

A survey of T cell repertoire evolution in the tumors, healthy tissue and blood of patients with early-stage untreated lung cancer offers an opportunity to monitor and identify neoantigen-specific T cells for personalized immunotherapy.

Kroopa Joshi
Marc Robert de Massy
Benny Chain
Research07 Oct 2019
Nature Medicine

Volume: 25, P: 1549-1559
The evolution of non-small cell lung cancer metastases in TRACERx

A longitudinal evolutionary analysis of 126 lung cancer patients with metastatic disease reveals the timing of metastatic divergence, modes of dissemination and the genomic events subject to selection during the metastatic transition.

Maise Al Bakir
Ariana Huebner
Charles Swanton
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 534-542
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer

Wu et al. utilize multiparametric analysis of early-stage human NSCLC to characterize a population of Vδ1 T cells displaying a resident memory and effector memory phenotype, which were associated with ongoing remission.

Yin Wu
Dhruva Biswas
Charles Swanton
ResearchOpen Access30 May 2022
Nature Cancer

Volume: 3, P: 696-709
Using DNA sequencing data to quantify T cell fraction and therapy response

A robust, cost-effective technique based on whole-exome sequencing data can be used to characterize immune infiltrates, relate the extent of these infiltrates to somatic changes in tumours, and enables prediction of tumour responses to immune checkpoint inhibition therapy.

Robert Bentham
Kevin Litchfield
Nicholas McGranahan
Research08 Sept 2021
Nature

Volume: 597, P: 555-560
Genomic–transcriptomic evolution in lung cancer and metastasis

Computational and machine-learning approaches that integrate genomic and transcriptomic variation from paired primary and metastatic non-small cell lung cancer samples from the TRACERx cohort reveal the role of transcriptional events in tumour evolution.

Carlos Martínez-Ruiz
James R. M. Black
Nicholas McGranahan
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 543-552
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Measurements of subclonal expansion of ctDNA in the plasma before surgery may enable the prediction of future metastatic subclones, offering the possibility for early intervention in patients with non-small-cell lung cancer.

Christopher Abbosh
Alexander M. Frankell
Charles Swanton
Research13 Apr 2023
Nature

Volume: 616, P: 553-562
The evolution of lung cancer and impact of subclonal selection in TRACERx

Analyses of multiregional tumour samples from 421 patients with non-small cell lung cancer prospectively enrolled to the TRACERx study reveal determinants of tumour evolution and relationships between intratumour heterogeneity and clinical outcome.

Alexander M. Frankell
Michelle Dietzen
Charles Swanton
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 525-533
Antibodies against endogenous retroviruses promote lung cancer immunotherapy

In lung adenocarcinoma, antibodies against endogenous retroviruses promote anti-tumour activity, and expression of endogenous retroviruses can predict outcomes of immunotherapy.

Kevin W. Ng
Jesse Boumelha
George Kassiotis
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 563-573
Carbohydrates and carbohydrate degradation gene abundance and transcription in Atlantic waters of the Arctic

Taylor Priest
Silvia Vidal-Melgosa
Bernhard M. Fuchs
ResearchOpen Access09 Dec 2023
ISME Communications

Volume: 3, P: 1-13
Amorphous solid dispersions of enzalutamide and novel polysaccharide derivatives: investigation of relationships between polymer structure and performance

Venecia R. Wilson
Xiaochun Lou
Lynne S. Taylor
ResearchOpen Access28 Oct 2020
Scientific Reports

Volume: 10, P: 1-12
Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

Kroopa Joshi
Marc Robert de Massy
Benny Chain
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1148
Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

Francesca Chemi
Dominic G. Rothwell
Jason Lester
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1147
A clonal expression biomarker associates with lung cancer mortality

TRACERx Lung: Intratumoral transcriptional heterogeneity, which often hinders the development of clinically useful RNA-expression-biased biomarkers for cancer, can now be overcome with an approach for the identification of clonal expression biomarkers.

Dhruva Biswas
Nicolai J. Birkbak
Angeles Montero
Research07 Oct 2019
Nature Medicine

Volume: 25, P: 1540-1548
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

Pulmonary venous tumor cells disseminating before tumor resection are heterogeneous, predict relapse and seed future metastasis of lung cancer

Francesca Chemi
Dominic G. Rothwell
Jason Lester
Research07 Oct 2019
Nature Medicine

Volume: 25, P: 1534-1539
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma

Yuan and colleagues developed an artificial intelligence-based method to derive growth patterns and morphological features from hematoxylin and eosin-stained slides of lung adenocarcinoma samples, for improved tumor grading and patient prognostication.

Xiaoxi Pan
Khalid AbdulJabbar
David A. Moore
ResearchOpen Access10 Jan 2024
Nature Cancer

Volume: 5, P: 347-363
Publisher Correction: A clonal expression biomarker associates with lung cancer mortality

Dhruva Biswas
Nicolai J. Birkbak
Angeles Montero
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1148
The T cell differentiation landscape is shaped by tumour mutations in lung cancer

Ghorani et al. use a multiomics approach to characterize the effect of tumour mutational burden on the differentiation of CD4 and CD8 T cell subpopulations in non-small cell lung cancer.

Ehsan Ghorani
James L. Reading
Sergio A. Quezada
Research22 May 2020
Nature Cancer

Volume: 1, P: 546-561
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma

Multiregion spatial histology, exome and transcriptome data from patients with non-small cell lung cancer suggest that cancer subclones from immune cold regions diversify later than subclones from immune hot regions

Khalid AbdulJabbar
Shan E. Ahmed Raza
Yinyin Yuan
Research27 May 2020
Nature Medicine

Volume: 26, P: 1054-1062
Application of smart solid lipid nanoparticles to enhance the efficacy of 5-fluorouracil in the treatment of colorectal cancer

Taylor Smith
Kevin Affram
Edward Agyare
ResearchOpen Access12 Oct 2020
Scientific Reports

Volume: 10, P: 1-14
Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx

Alexander M. Frankell
Michelle Dietzen
Charles Swanton
Amendments and CorrectionsOpen Access04 Jul 2024
Nature

Volume: 631, P: E15
A history of the optic nerve and its diseases

C Reeves
D Taylor
Research08 Nov 2004
Eye

Volume: 18, P: 1096-1109
Solar-driven reforming of solid waste for a sustainable future

Photoreforming is a sunlight-driven technology that can simultaneously reclaim the value in waste and contribute to renewable hydrogen production. This Review examines the advantages and challenges and identifies ways forward.

Taylor Uekert
Christian M. Pichler
Erwin Reisner
Reviews30 Nov 2020
Nature Sustainability

Volume: 4, P: 383-391
Atlantic water influx and sea-ice cover drive taxonomic and functional shifts in Arctic marine bacterial communities

Taylor Priest
Wilken-Jon von Appen
Matthias Wietz
ResearchOpen Access08 Jul 2023
The ISME Journal

Volume: 17, P: 1612-1625
High abundance of hydrocarbon-degrading Alcanivorax in plumes of hydrothermally active volcanoes in the South Pacific Ocean

Bledina Dede
Taylor Priest
Anke Meyerdierks
ResearchOpen Access31 Jan 2023
The ISME Journal

Volume: 17, P: 600-610
Niche partitioning of the ubiquitous and ecologically relevant NS5 marine group

Taylor Priest
Anneke Heins
Bernhard M. Fuchs
ResearchOpen Access15 Feb 2022
The ISME Journal

Volume: 16, P: 1570-1582

Search

Filter By:

Search

Quick links