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Showing 1–1 of 1 results
Advanced filters: Author: Teide Jens Boysen Clear advanced filters
  • Patients with a mutant thyroid hormone receptor α1 are treated with high-dose thyroxine, but their heart rate remains low. Here, the authors show that the mutant receptor triggers cardiac reprogramming in the embryo, which prevents the response of specific ion channels and heart rate to the hormone.

    • Riccardo Dore
    • Laura Watson
    • Jens Mittag
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11