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Advanced filters: Author: Thangaselvam Muthusamy Clear advanced filters

  • In xenograft tumour models in mice, modulation of dietary serine, serine palmitoyltransferase or phosphoglycerate dehydrogenase activity enables control of the endogenous synthesis of deoxysphingolipids, sensitizing the tumours to metabolic stress and slowing their progression.

    • Thangaselvam Muthusamy
    • Thekla Cordes
    • Christian M. Metallo
    Research
    Nature
    Volume: 586, P: 790-795