Transposon directed insertion–site sequencing (TraDIS) is used to identify T6SS toxins in Pseudomonas aeruginosa, leading to the discovery of Tse8 as a protein that is delivered to target cells where it alters the stoichiometry of the transamidosome complex and thereby inhibits protein synthesis.
- Laura M. Nolan
- Amy K. Cain
- Alain Filloux
