Nature Search

Growth form and lifespan of herbaceous species mediate the role of traits in short-term drought response

Using 63 globally distributed grassland and shrubland sites from the International Drought Experiment, this study identified plant traits linked to drought resistance after 1 year of extreme drought across growth forms, lifespans and climate.

Samantha J. Worthy
Justin C. Luong
Jennifer L. Funk
Research11 Feb 2026
Nature Ecology & Evolution

P: 1-11
Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin

Olivier Spertini
Geoffrey S. Kansas
Thomas F. Tedder
Research21 Feb 1991
Nature

Volume: 349, P: 691-694
Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes

David I. Watkins
Zheng W. Chen
Norman L. Letvin
Research05 Jul 1990
Nature

Volume: 346, P: 60-63
HIV clearance in an infant?

M. O. McClure
P. D. Bieniasz
E. C. Holmes
Research22 Jun 1995
Nature

Volume: 375, P: 637
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

IL-21- and CD40-dependent cognate interactions with T cells are identified as key drivers for the generation of IL-10-producing regulatory B cells, which can protect against autoimmune disease.

Ayumi Yoshizaki
Tomomitsu Miyagaki
Thomas F. Tedder
Research14 Oct 2012
Nature

Volume: 491, P: 264-268
CD19: a promising B cell target for rheumatoid arthritis

Monoclonal antibodies directed against CD20 have emerged as an effective therapy for RA. Using this approach to target CD19 could provide a greater breadth of B-cell depletion with additional therapeutic benefits.

Thomas F. Tedder
Reviews01 Oct 2009
Nature Reviews Rheumatology

Volume: 5, P: 572-577
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

Edgar Engleman and his colleagues show that B cell production of pathogenic IgG antibodies is involved in obesity-induced insulin resistance. They also show that B cell depletion in obese mice ameliorates metabolic disease, and that obese, insulin-resistant humans have a unique profile of IgG autoantibodies. These results suggest a possible new therapeutic target to treat insulin resistance.

Daniel A Winer
Shawn Winer
Edgar G Engleman
Research17 Apr 2011
Nature Medicine

Volume: 17, P: 610-617
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila

Thomas E. Crowley
Timothy Hoey
Robert Tjian
Research11 Feb 1993
Nature

Volume: 361, P: 557-561
Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

Thomas E. Wellems
Lindsey J. Panton
Donald J. Krogstad
Research17 May 1990
Nature

Volume: 345, P: 253-255
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms

Jonathan C Poe
Yoko Fujimoto
Thomas F Tedder
Research19 Sept 2004
Nature Immunology

Volume: 5, P: 1078-1087
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Correction: Autoimmunity: Regulatory B cells—IL-35 and IL-21 regulate the regulators

Thomas F. Tedder
Warren J. Leonard
Amendments and Corrections16 Sept 2014
Nature Reviews Rheumatology

Volume: 10, P: 636
Adeno-associated virus 2 infection in children with non-A–E hepatitis

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Antonia Ho
Richard Orton
Emma C. Thomson
Research30 Mar 2023
Nature

Volume: 617, P: 555-563
T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination

T cell responses can be generated to either pathogen infection or from priming with a vaccine. Here the authors compare T cell generation, phenotype and single cell transcriptome of participants vaccinated with a mpox vaccine or infected with the virus showing that the virus induced T cells showed more effective function and phenotype.

Ji-Li Chen
Beibei Wang
Tao Dong
ResearchOpen Access10 May 2025
Nature Communications

Volume: 16, P: 1-17
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

Benedict D. Michael
Cordelia Dunai
David K. Menon
ResearchOpen Access22 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Regulatory B cells—IL-35 and IL-21 regulate the regulators

IL-21 regulates the activity and number of IL-10-producing regulatory B cells (B10 cells) that modulate immune responses and limit diverse autoimmune diseases. A new study demonstrates that IL-35 has a similar function. Identifying regulatory circuits that control B10-cell function in vivo might open the door to future treatments for autoimmune diseases.

Thomas F. Tedder
Warren J. Leonard
News & Views17 Jun 2014
Nature Reviews Rheumatology

Volume: 10, P: 452-453
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Gas-Phase Reactions of the Halogens and their Compounds

J. H. THOMAS
E. WHITTLE
News08 Jul 1961
Nature

Volume: 191, P: 129-131
B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction

After myocardial infarction, inflammatory cells are rapidly recruited to the heart and strongly affect the course of recovery. Ziad Mallat and his colleagues uncover a pathogenic role for B cells after myocardial infarction, showing that infarction triggers B cell secretion of the chemokine Ccl7, which mobilizes monocytes from the bone marrow, increases their recruitment to the heart and impairs heart function.

Yasmine Zouggari
Hafid Ait-Oufella
Ziad Mallat
Research15 Sept 2013
Nature Medicine

Volume: 19, P: 1273-1280
Seroprevalence of human herpesvirus-8 (HHV-8) in countries of Southeast Asia compared to the USA, the Caribbean and Africa

D Ablashi
L Chatlynne
C Boshoff
ResearchOpen Access15 Oct 1999
British Journal of Cancer

Volume: 81, P: 893-897
Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

Benedict D. Michael
Cordelia Dunai
David K. Menon
Amendments and CorrectionsOpen Access04 Apr 2024
Nature Communications

Volume: 15, P: 1
Trends in cancer incidence in Kyadondo County, Uganda, 1960–1997

H R Wabinga
D M Parkin
S Nambooze
ResearchOpen Access04 Apr 2000
British Journal of Cancer

Volume: 82, P: 1585-1592
ARID2-related disorder: further delineation of the clinical phenotype of 27 novel individuals and description of an epigenetic signature

Clara Houdayer
Kathleen Rooney
Estelle Colin
ResearchOpen Access05 Mar 2025
European Journal of Human Genetics

Volume: 33, P: 1422-1431
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
Quantifying neutralising antibody responses against SARS-CoV-2 in dried blood spots (DBS) and paired sera

Kelly J. Roper
Jordan Thomas
Georgios Pollakis
ResearchOpen Access11 Sept 2023
Scientific Reports

Volume: 13, P: 1-12
Intravital imaging of Ca²⁺ signals in lymphocytes of Ca²⁺ biosensor transgenic mice: indication of autoimmune diseases before the pathological onset

Soichiro Yoshikawa
Takako Usami
Takahiro Adachi
ResearchOpen Access06 Jan 2016
Scientific Reports

Volume: 6, P: 1-13
Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells

Padmapriya Ponnuswamy
Jeremie Joffre
Hafid Ait-Oufella
ResearchOpen Access23 Jun 2017
Scientific Reports

Volume: 7, P: 1-10
Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function

D J DiLillo
J B Weinberg
T F Tedder
Research13 Jul 2012
Leukemia

Volume: 27, P: 170-182
The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease

Pablo Engel
Michael J. Eck
Cox Terhorst
Reviews01 Oct 2003
Nature Reviews Immunology

Volume: 3, P: 813-821
Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

Jonathan E. Millar
Lucile Neyton
Peter Young
ResearchOpen Access27 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
Harmonization of Zika neutralization assays by using the WHO International Standard for anti-Zika virus antibody

Giada Mattiuzzo
Ivana Knezevic
Rafael De La Barrera
ResearchOpen Access14 Oct 2019
npj Vaccines

Volume: 4, P: 1-9

Search

Growth form and lifespan of herbaceous species mediate the role of traits in short-term drought response

Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin

Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes

HIV clearance in an infant?

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

CD19: a promising B cell target for rheumatoid arthritis

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

Mapping the human genetic architecture of COVID-19

A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila

Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

Genomic investigations of unexplained acute hepatitis in children

CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms

Genetic mechanisms of critical illness in COVID-19

Correction: Autoimmunity: Regulatory B cells—IL-35 and IL-21 regulate the regulators

Adeno-associated virus 2 infection in children with non-A–E hepatitis

T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

Regulatory B cells—IL-35 and IL-21 regulate the regulators

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Gas-Phase Reactions of the Halogens and their Compounds

B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction

Seroprevalence of human herpesvirus-8 (HHV-8) in countries of Southeast Asia compared to the USA, the Caribbean and Africa

Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

Trends in cancer incidence in Kyadondo County, Uganda, 1960–1997

ARID2-related disorder: further delineation of the clinical phenotype of 27 novel individuals and description of an epigenetic signature

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Quantifying neutralising antibody responses against SARS-CoV-2 in dried blood spots (DBS) and paired sera

Intravital imaging of Ca²⁺ signals in lymphocytes of Ca²⁺ biosensor transgenic mice: indication of autoimmune diseases before the pathological onset

Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells

Chronic lymphocytic leukemia and regulatory B cells share IL-10 competence and immunosuppressive function

The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease

Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study

Harmonization of Zika neutralization assays by using the WHO International Standard for anti-Zika virus antibody

Search

Quick links

Search

Filter By:

Search

Quick links