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Showing 1–3 of 3 results
Advanced filters: Author: Thomas Hägglöf Clear advanced filters

  • Although rare, antibodies against the receptor-binding domain of SARS-CoV-2 that showed potent antiviral activity were obtained from all tested convalescent individuals, suggesting that a vaccine designed to elicit such antibodies could be broadly effective.

    • Davide F. Robbiani
    • Christian Gaebler
    • Michel C. Nussenzweig
    Research
    Nature
    Volume: 584, P: 437-442

  • In a cohort of 87 individuals with COVID-19, the memory B cell response at 6.2 months after the onset of disease evolves in a manner that is consistent with the persistence of SARS-CoV-2 antigen.

    • Christian Gaebler
    • Zijun Wang
    • Michel C. Nussenzweig
    Research
    Nature
    Volume: 591, P: 639-644

  • The cytokine IL-18 can drive autoantibody production. Karlsson and colleagues show that such responses are limited by a three-way cellular interaction whereby splenic neutrophils activate both B cells and invariant natural killer T cells but the activated B cells are killed by FasL+ invariant natural killer T cells.

    • Thomas Hägglöf
    • Saikiran K Sedimbi
    • Mikael C I Karlsson
    Research
    Nature Immunology
    Volume: 17, P: 1407-1414