Resveratrol intervention improves lipid homeostasis, but how it can target multiple organs with very low bioavailability remains elusive. Here, the authors report that gut microbiota-bile acids are linked to the hypolipidemic effect of resveratrol via inhibiting the intestinal FXR/SR-B1 signalling pathway.
- Juan Pang
- Fitore Raka
- Tianru Jin