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Showing 1–1 of 1 results
Advanced filters: Author: Tilka Fannana Clear advanced filters
  • Serotonin 5-HT2A receptor signaling mechanisms associated with predicting psychedelic potential remain elusive. Using 5-HT2A-selective β-arrestin-biased ligands, here the authors show that a threshold level of 5-HT2A-Gq efficacy and not β-arrestin recruitment is associated with psychedelic potential.

    • Jason Wallach
    • Andrew B. Cao
    • John D. McCorvy
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19