Nature Search

Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission

Post-international travel quarantine has been widely implemented to mitigate SARS-CoV-2 transmission, but the impacts of such policies are unclear. Here, the authors used linked genomic and contact tracing data to assess the impacts of a 14-day quarantine on return to England in summer 2020.

Dinesh Aggarwal
Andrew J. Page
Ewan M. Harrison
ResearchOpen Access23 Feb 2022
Nature Communications

Volume: 13, P: 1-13
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

Genetic and testing data from England show that the SARS-CoV-2 variant of concern B.1.1.7 has a transmission advantage over other lineages.

Erik Volz
Swapnil Mishra
Neil M. Ferguson
Research25 Mar 2021
Nature

Volume: 593, P: 266-269
SARS-CoV-2 evolution during treatment of chronic infection

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Research05 Feb 2021
Nature

Volume: 592, P: 277-282
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Research11 Mar 2021
Nature

Volume: 593, P: 136-141
Multidisciplinary evidence for early banana (Musa cvs.) cultivation on Mabuyag Island, Torres Strait

Multiproxy archaeobotanical analyses of an abandoned agricultural terrace at Wagadagam document extensive, low-intensity forms of plant management from at least 2,145–1,930 cal yr bp and intensive forms of cultivation at 1,376–1,293 cal yr bp.

Robert N. Williams
Duncan Wright
Tim Denham
Research10 Aug 2020
Nature Ecology & Evolution

Volume: 4, P: 1342-1350
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

In this study, Aggarwal and colleagues perform prospective sequencing of SARS-CoV-2 isolates derived from asymptomatic student screening and symptomatic testing of students and staff at the University of Cambridge. They identify important factors that contributed to within university transmission and onward spread into the wider community.

Dinesh Aggarwal
Ben Warne
Ian G. Goodfellow
ResearchOpen Access08 Feb 2022
Nature Communications

Volume: 13, P: 1-16
Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

Ming Chen
Darrell J. Tomkins
Manuel Buchwald
Research01 Apr 1996
Nature Genetics

Volume: 12, P: 448-451
The function of zebra stripes

The function of zebra stripes remains unclear as none of the options have been validated ecologically. Here, the authors, matching striping patterns to environmental variables, test the main hypotheses against each other and find that biting fly avoidance best explains the presence of stripes in equids.

Tim Caro
Amanda Izzo
Theodore Stankowich
Research01 Apr 2014
Nature Communications

Volume: 5, P: 1-10
Defining the role of common variation in the genomic and biological architecture of adult human height

Timothy Frayling, Joel Hirschhorn, Peter Visscher and colleagues report a meta-analysis of genome-wide association studies for adult height in 253,288 individuals. They identify 697 variants in 423 loci significantly associated with adult height and find that these variants cluster in pathways involved in growth and together explain one-fifth of the heritability for this trait.

Andrew R Wood
Tonu Esko
Timothy M Frayling
Research05 Oct 2014
Nature Genetics

Volume: 46, P: 1173-1186
New genetic loci link adipose and insulin biology to body fat distribution

Genome-wide association meta-analyses of waist-to-hip ratio adjusted for body mass index in more than 224,000 individuals identify 49 loci, 33 of which are new and many showing significant sexual dimorphism with a stronger effect in women; pathway analyses implicate adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution.

Dmitry Shungin
Thomas W. Winkler
Karen L Mohlke
Research11 Feb 2015
Nature

Volume: 518, P: 187-196
Genetic studies of body mass index yield new insights for obesity biology

A genome-wide association study and Metabochip meta-analysis of body mass index (BMI) detects 97 BMI-associated loci, of which 56 were novel, and many loci have effects on other metabolic phenotypes; pathway analyses implicate the central nervous system in obesity susceptibility and new pathways such as those related to synaptic function, energy metabolism, lipid biology and adipogenesis.

Adam E. Locke
Bratati Kahali
Elizabeth K. Speliotes
Research11 Feb 2015
Nature

Volume: 518, P: 197-206
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Patricia Munroe, Christopher Newton-Cheh, Andrew Morris and colleagues perform association studies in over 340,000 individuals of European ancestry and identify 66 loci, of which 17 are novel, involved in blood pressure regulation. The risk SNPs are enriched for cis-regulatory elements, particularly in vascular endothelial cells.

Georg B Ehret
Teresa Ferreira
Patricia B Munroe
Research12 Sept 2016
Nature Genetics

Volume: 48, P: 1171-1184
The genetic architecture of type 2 diabetes

Sequencing data from two large-scale studies show that most of the genetic variation influencing the risk of type 2 diabetes involves common alleles and is found in regions previously identified by genome-wide association studies, clarifying the genetic architecture of this disease.

Christian Fuchsberger
Jason Flannick
Mark I. McCarthy
Research11 Jul 2016
Nature

Volume: 536, P: 41-47
A general approach to 3D-printed single-atom catalysts

Single-atom catalysts (SACs) are attractive for a variety of applications but their synthesis remains challenging. Now, a scalable and economical 3D-printing approach has been developed for producing libraries of SACs using a variety of metals, coordination environments and spatial geometries.

Fangxi Xie
Xiaolin Cui
Shi-Zhang Qiao
Research02 Jan 2023
Nature Synthesis

Volume: 2, P: 129-139
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
[¹⁸F]Difluorocarbene for positron emission tomography

Carbene chemistry is used to introduce difluoromethyl groups labelled with fluorine-18 into compounds for positron emission tomography imaging, using a reagent designed for high molar activity and versatility.

Jeroen B. I. Sap
Claudio F. Meyer
Véronique Gouverneur
Research28 Mar 2022
Nature

Volume: 606, P: 102-108
Discovery and refinement of loci associated with lipid levels

Cristen Willer and colleagues report genome-wide association analyses for blood lipid levels in 188,578 individuals. They identify 62 loci newly associated with blood lipid levels, refine the association signals at 12 loci and examine associations with cardiovascular and metabolic traits.

Cristen J Willer
Ellen M Schmidt
Gonçalo R Abecasis
Research06 Oct 2013
Nature Genetics

Volume: 45, P: 1274-1283
Temperature contributes to host specialization of coffee wilt disease (Fusarium xylarioides) on arabica and robusta coffee crops

Xiuhan Zhang
Lily D. Peck
Timothy G. Barraclough
ResearchOpen Access08 Jun 2023
Scientific Reports

Volume: 13, P: 1-12
Common variants associated with plasma triglycerides and risk for coronary artery disease

Sekar Kathiresan and colleagues examine 185 common variants using a modified mendelian randomization approach and provide evidence supporting a causal role of triglyceride-rich lipoproteins in the development of coronary artery disease.

Ron Do
Cristen J Willer
Sekar Kathiresan
Research06 Oct 2013
Nature Genetics

Volume: 45, P: 1345-1352
Selection for high levels of resistance to double-stranded RNA (dsRNA) in Colorado potato beetle (Leptinotarsa decemlineata Say) using non-transgenic foliar delivery

Swati Mishra
James Dee
Juan Luis Jurat-Fuentes
ResearchOpen Access22 Mar 2021
Scientific Reports

Volume: 11, P: 1-12
Effect of statin therapy on plasma C-type Natriuretic Peptides and Endothelin-1 in males with and without symptomatic coronary artery disease

Timothy C. R. Prickett
Richard W. Troughton
Eric A. Espiner
ResearchOpen Access13 May 2020
Scientific Reports

Volume: 10, P: 1-9
Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Jason Flannick
Christian Fuchsberger
Mark I. McCarthy
Amendments and CorrectionsOpen Access23 Jan 2018
Scientific Data

Volume: 5, P: 1-2
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Jason Flannick
Christian Fuchsberger
Mark I. McCarthy
ResearchOpen Access19 Dec 2017
Scientific Data

Volume: 4, P: 1-22

Search

Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission

Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England

SARS-CoV-2 evolution during treatment of chronic infection

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Multidisciplinary evidence for early banana (Musa cvs.) cultivation on Mabuyag Island, Torres Strait

Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

The function of zebra stripes

Defining the role of common variation in the genomic and biological architecture of adult human height

New genetic loci link adipose and insulin biology to body fat distribution

Genetic studies of body mass index yield new insights for obesity biology

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

The genetic architecture of type 2 diabetes

A general approach to 3D-printed single-atom catalysts

Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

[¹⁸F]Difluorocarbene for positron emission tomography

Discovery and refinement of loci associated with lipid levels

Temperature contributes to host specialization of coffee wilt disease (Fusarium xylarioides) on arabica and robusta coffee crops

Common variants associated with plasma triglycerides and risk for coronary artery disease

Selection for high levels of resistance to double-stranded RNA (dsRNA) in Colorado potato beetle (Leptinotarsa decemlineata Say) using non-transgenic foliar delivery

Effect of statin therapy on plasma C-type Natriuretic Peptides and Endothelin-1 in males with and without symptomatic coronary artery disease

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

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