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Nature Biotechnology (3)

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Showing 1–3 of 3 results

Advanced filters: Author: Tim L Setter Clear advanced filters

Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index

The in vivo efficacy of antibody-drug conjugates is enhanced by decreasing their hydrophobicity.

Robert P Lyon
Tim D Bovee
Peter D Senter
Research15 Jun 2015
Nature Biotechnology

Volume: 33, P: 733-735
Sequencing wild and cultivated cassava and related species reveals extensive interspecific hybridization and genetic diversity

The global genetic diversity of cassava and related Manihot species is revealed by sequencing of 53 cultivated and wild accessions and genotyping of 268 African cassavas, providing a vital resource for breeding.

Jessen V Bredeson
Jessica B Lyons
Daniel S Rokhsar
ResearchOpen Access18 Apr 2016
Nature Biotechnology

Volume: 34, P: 562-570
Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates

A new method for linking antibodies to drugs produces conjugates with improved stability and efficacy.

Robert P Lyon
Jocelyn R Setter
Peter D Senter
Research07 Sept 2014
Nature Biotechnology

Volume: 32, P: 1059-1062