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Showing 1–50 of 169 results
Advanced filters: Author: Tim Reid Clear advanced filters

  • An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

    • Erola Pairo-Castineira
    • Konrad Rawlik
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 617, P: 764-768

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

    • Antonia Ho
    • Richard Orton
    • Emma C. Thomson
    Research
    Nature
    Volume: 617, P: 555-563

  • A graphene transistor has been built with high on/off ratios

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • Data collected from more than 2,000 taxa provide an unparalleled opportunity to quantify how extreme wildfires affect biodiversity, revealing that the largest effects on plants and animals were in areas with frequent or recent past fires and within extensively burnt areas.

    • Don A. Driscoll
    • Kristina J. Macdonald
    • Ryan D. Phillips
    ResearchOpen Access
    Nature
    Volume: 635, P: 898-905

  • Dense calcium imaging combined with co-registered high-resolution electron microscopy reconstruction of the brain of the same mouse provide a functional connectomics map of tens of thousands of neurons of a region of the primary cortex and higher visual areas.

    • J. Alexander Bae
    • Mahaly Baptiste
    • Chi Zhang
    ResearchOpen Access
    Nature
    Volume: 640, P: 435-447

  • Analysing camera-trap data of 163 mammal species before and after the onset of COVID-19 lockdowns, the authors show that responses to human activity are dependent on the degree to which the landscape is modified by humans, with carnivores being especially sensitive.

    • A. Cole Burton
    • Christopher Beirne
    • Roland Kays
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 8, P: 924-935

  • Combined patch clamp recording, biocytin staining and single-cell RNA-sequencing of human neurocortical neurons shows an expansion of glutamatergic neuron types relative to mouse that characterizes the greater complexity of the human neocortex.

    • Jim Berg
    • Staci A. Sorensen
    • Ed S. Lein
    ResearchOpen Access
    Nature
    Volume: 598, P: 151-158

  • Petrels are wide-ranging, highly threatened seabirds that often ingest plastic. This study used tracking data for 7,137 petrels of 77 species to map global exposure risk and compare regions, species, and populations. The results show higher exposure risk for threatened species and stress the need for international cooperation to tackle marine litter.

    • Bethany L. Clark
    • Ana P. B. Carneiro
    • Maria P. Dias
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Turajlic and colleagues assess longitudinal antibody and cellular immune responses against SARS-CoV-2 variants of concern in patients with cancer, following either recovery from SARS-CoV-2 infection or vaccination, in two back-to-back reports from the CAPTURE study.

    • Annika Fendler
    • Lewis Au
    • Samra Turajlic
    ResearchOpen Access
    Nature Cancer
    Volume: 2, P: 1321-1337

  • Genotype and exome sequencing of 150,000 participants and whole-genome sequencing of 9,950 selected individuals recruited into the Mexico City Prospective Study constitute a valuable, publicly available resource of non-European sequencing data.

    • Andrey Ziyatdinov
    • Jason Torres
    • Roberto Tapia-Conyer
    ResearchOpen Access
    Nature
    Volume: 622, P: 784-793

    • Tim Reid
    News & Views
    Nature Nanotechnology
    Volume: 3, P: 321

  • Researchers have performed simultaneous optical and electrical measurements on a single molecule

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • Incredibly tough composite materials have been made by mimicking the fine plate-like structure of mollusc shells

    • Tim Reid
    Research Highlights
    Nature Chemistry
    P: 1

    • Tim Reid
    News & Views
    Nature Nanotechnology
    Volume: 4, P: 481

  • The goal of the 1000 Genomes Project is to provide in-depth information on variation in human genome sequences. In the pilot phase reported here, different strategies for genome-wide sequencing, using high-throughput sequencing platforms, were developed and compared. The resulting data set includes more than 95% of the currently accessible variants found in any individual, and can be used to inform association and functional studies.

    • Richard M. Durbin
    • David Altshuler (Co-Chair)
    • Gil A. McVean
    ResearchOpen Access
    Nature
    Volume: 467, P: 1061-1073

  • A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

    • Erola Pairo-Castineira
    • Sara Clohisey
    • J. Kenneth Baillie
    Research
    Nature
    Volume: 591, P: 92-98

  • Specially designed thin films can fold themselves up into tiny boxes for storing microelectronic devices

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • New experimental evidence proves that ice can form at room temperature if it is confined in a very thin layer

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • Carbon nanotube pipettes can be used to release tiny amounts of copper iodide in a controlled fashion using electrical pulses

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • Detectors made from carbon nanotubes can identify signs of diseases using breath samples

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • New circuits that control the movement of excitons could directly link devices to photonic signals

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • Researchers have synthesized stable alkyl oxonium ions that could lead to new and interesting aromatic compounds

    • Tim Reid
    Research Highlights
    Nature Chemistry
    P: 1

  • Nanopatterning the surface of tiny bubbles can keep them stable for over a year

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • The electromagnetic fields in and around nanostructures can be visualized by combining electron microscopy with intense optical pulses.

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • A new type of transistor built from a carbon nanotube is capable of detecting the transfer of individual electrons

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • Hot iron nanoparticles could be used to carve electronic circuits out of graphene sheets

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • A simple technique that uses silicon templates produces ultrasmooth metal films for transporting surface plasmons

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1

  • Strands of DNA perform remarkable acrobatics to wrap themselves around carbon nanotubes, forming very useful hybrid structures

    • Tim Reid
    Research Highlights
    Nature Nanotechnology
    P: 1