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Advanced filters: Author: Timon Damelang Clear advanced filters

Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection

Chronic viral infection leads to a dysregulation of germinal center B cell responses. Di Pietro et al. show that the epigenetic modifier BMI-1 promotes this dysfunctional response and that targeting BMI-1 in B cells can restore humoral immunity and accelerate viral clearance.

Andrea Di Pietro
Jack Polmear
Kim L. Good-Jacobson
Research29 Nov 2021
Nature Immunology

Volume: 23, P: 86-98
Antibody mediated activation of natural killer cells in malaria exposed pregnant women

Timon Damelang
Elizabeth H. Aitken
Amy W. Chung
ResearchOpen Access18 Feb 2021
Scientific Reports

Volume: 11, P: 1-16

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Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection

Antibody mediated activation of natural killer cells in malaria exposed pregnant women

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