Mounting evidence suggests that gastrointestinal surgical procedures, such as gastric bypass, can induce long-term remission of type 2 diabetes mellitus (T2DM) and other metabolic disorders. Here, Rubino and colleagues provide an overview of the use of 'metabolic surgery' for patients with T2DM and discuss the implications for future research. The authors hypothesize that the gastrointestinal tract might have a key role in the pathophysiology of T2DM and obesity.
- Francesco Rubino
- Sarah L. R'bibo
- Timothy E. McGraw
