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Showing 1–4 of 4 results
Advanced filters: Author: Tina Pangršič Clear advanced filters

  • Harmonin was previously identified as a scaffolding protein that is important for the localization of cadherin in the upper tip-link density of the stereociliary membrane and for the initial mechanotransduction event in inner hair cells. Here the authors find that harmonin is involved in regulating the voltage-gated calcium channel for synaptic transmission in inner hair cell ribbon synapses.

    • Frederick D Gregory
    • Keith E Bryan
    • Amy Lee
    Research
    Nature Neuroscience
    Volume: 14, P: 1109-1111

  • In addition to the morphological difference, inner hair cell (IHC) synapses do not have the full complement of neuronal SNARE proteins found in other types of synapses. Here, Nouvian et al. provide a series of empirical evidence that shows that exocytosis in IHCs occurs independently of neuronal SNARE proteins.

    • Régis Nouvian
    • Jakob Neef
    • Tobias Moser
    Research
    Nature Neuroscience
    Volume: 14, P: 411-413

  • The inner hair cells (IHCs) within the cochlea convey sound information and have been thought to be electrically and metabolically independent from each other. Here authors report that a subset of IHCs are electrochemically coupled in ‘mini-syncytia’.

    • Philippe Jean
    • Tommi Anttonen
    • Tobias Moser
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14