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Showing 1–5 of 5 results
Advanced filters: Author: Tobias Eichlisberger Clear advanced filters

  • How basolateral amygdala represents the specific value of rewards remains unclear. Here the authors find that basolateral amygdala neurons assign stimulus-specific values to different rewards and rapidly re-scale these signals with changing reward context, thirst or stress, illuminating how the brain guides flexible, state-dependent choices.

    • Julian Hinz
    • Mathias Mahn
    • Andreas Lüthi
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12

  • Deep-brain calcium imaging of mice engaged in social or spatial exploration reveals that these state-dependent behaviours are encoded by distinct neuronal ensembles of the basolateral amygdala.

    • Maria Sol Fustiñana
    • Tobias Eichlisberger
    • Andreas Lüthi
    Research
    Nature
    Volume: 592, P: 267-271

  • Group 3 innate lymphoid cells (ILC3s) promote T cell activation in the spleen but suppress it in the gut. Here, the authors show that this distinct regulation is mediated by gut microbiota-induced IL-23 and IFN-γ, respectively, and, along with the article by Rao et al, this work elucidates how cytokines set context specificity of ILC-T cell crosstalk by regulating ILC antigen presentation.

    • Frank Michael Lehmann
    • Nicole von Burg
    • Daniela Finke
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15

  • Krabbe, Paradiso et al. show that amygdala VIP interneurons are activated by instructive cues for associative learning. These interneurons provide a mandatory disinhibitory signal permitting plasticity in response to unexpected salient events.

    • Sabine Krabbe
    • Enrica Paradiso
    • Andreas Lüthi
    Research
    Nature Neuroscience
    Volume: 22, P: 1834-1843

  • PIK3CA mutations are associated with distinct types of human breast cancers but the cellular origin and mechanisms responsible for this heterogeneity were unclear; here, using a genetic approach in mice, the PIK3CAH1047R mutation is shown to induce multipotent stem-like cells and mammary tumours with different levels of malignancy depending on the cell of origin.

    • Shany Koren
    • Linsey Reavie
    • Mohamed Bentires-Alj
    Research
    Nature
    Volume: 525, P: 114-118