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T and B cell responses against Epstein–Barr virus in primary sclerosing cholangitis

Interrogation of electronic health records and the B and T cell repertoires of people with PSC shows a link between Epstein–Barr virus and primary sclerosing cholangitis, an incurable autoimmune liver disease.

Hesham ElAbd
Mitchell Pesesky
Andre Franke
ResearchOpen Access11 Jun 2025
Nature Medicine

Volume: 31, P: 2306-2316
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

Tom Karlsen and colleagues report a genome-wide association study for primary sclerosing cholangitis, a chronic bile duct disease. They identify susceptibility loci at MST1 and near BCL2L11.

Espen Melum
Andre Franke
Tom H Karlsen
Research12 Dec 2010
Nature Genetics

Volume: 43, P: 17-19
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Konstantinos Lazaridis, Carl Anderson and colleagues report results of a genome-wide association study of primary sclerosing cholangitis (PSC). They identify four new susceptibility loci for PSC and quantify the correlation of common genetic variation shared between PSC and inflammatory bowel diseases.

Sun-Gou Ji
Brian D Juran
Carl A Anderson
Research19 Dec 2016
Nature Genetics

Volume: 49, P: 269-273
Impact of regular additional endobiliary radiofrequency ablation on survival of patients with advanced extrahepatic cholangiocarcinoma under systemic chemotherapy

Maria A. Gonzalez-Carmona
Christian Möhring
Tobias J. Weismüller
ResearchOpen Access19 Jan 2022
Scientific Reports

Volume: 12, P: 1-11
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Tom Karlsen and colleagues report an association study for primary sclerosing cholangitis (PSC), a severe liver disease, using the Immunochip array. They identify nine loci newly associated with PSC and examine pleiotropy with other autoimmune disorders.

Jimmy Z Liu
Johannes Roksund Hov
Tom H Karlsen
Research21 Apr 2013
Nature Genetics

Volume: 45, P: 670-675
Transpapillary tissue sampling of biliary strictures: balloon dilatation prior to forceps biopsy improves sensitivity and accuracy

Daniel Pörner
Dominik J. Kaczmarek
Tobias J. Weismüller
ResearchOpen Access15 Oct 2020
Scientific Reports

Volume: 10, P: 1-9

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T and B cell responses against Epstein–Barr virus in primary sclerosing cholangitis

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

Impact of regular additional endobiliary radiofrequency ablation on survival of patients with advanced extrahepatic cholangiocarcinoma under systemic chemotherapy

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Transpapillary tissue sampling of biliary strictures: balloon dilatation prior to forceps biopsy improves sensitivity and accuracy

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