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Showing 1–4 of 4 results
Advanced filters: Author: Todd A Duncombe Clear advanced filters

  • Circulating tumour cells (CTCs) are rare cells found in the blood of certain cancer patients. Here, the authors develop a cytometry tool that appends a microfluidic western blot to a CTC isolation workflow and apply it to profile a panel of proteins in single CTCs isolated from ER+ breast cancer patients.

    • Elly Sinkala
    • Elodie Sollier-Christen
    • Amy E. Herr
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12

  • The unique physical and chemical properties of microfluidic devices have underpinned notable recent advances in molecular cell biology research and will facilitate a new era of biological enquiry of increased precision.

    • Todd A. Duncombe
    • Augusto M. Tentori
    • Amy E. Herr
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 16, P: 554-567

  • Simon Bachler et al. present a new microfluidic platform to control the precise position and patterns of nanoliter droplets with various lipid materials. They show their platform enables monitoring of droplets and subsequent label-free mass spectrometry, which represents an important advance for the synthetic biology community.

    • Simon Bachler
    • Dominik Haidas
    • Petra S. Dittrich
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-9

  • Single-cell-resolution western blotting concatenates an electrophoretic separation to downstream immunoprobing of unfixed mammalian cells to detect proteins, isoforms, and interactions that are not discernable by immunoreactivity alone.

    • Chi-Chih Kang
    • Kevin A Yamauchi
    • Amy E Herr
    Protocols
    Nature Protocols
    Volume: 11, P: 1508-1530