Nature Search

Oxidative Phosphorylation: A Chemical Approach Using Quinol Phosphates

V. M. CLARK
G. W. KIRBY
ALEXANDER TODD
Research14 Jun 1958
Nature

Volume: 181, P: 1650-1652
Ancient co-option of LTR retrotransposons as yeast centromeres

Evolutionarily related ‘proto-point’ centromeres providing resolution to the evolutionary origins of point centromeres are identified in yeast, and comparison shows they evolved in an ancestor with retrotransposon-rich centromeres and that long-terminal-repeat retrotransposons are the genetic substrate.

Max A. B. Haase
Luciana Lazar-Stefanita
Jef D. Boeke
ResearchOpen Access18 Feb 2026
Nature

P: 1-8
The Dryad Digital Repository: Published evolutionary data as part of the greater data ecosystem

Todd Vision
ResearchOpen Access30 Jun 2010
Nature Precedings

P: 1
Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8⁺ T cells in lymph nodes

Conventional type 1 dendritic cells (cDC1) can boost the precursor exhausted T cell population thought to be essential for efficacy of immune checkpoint therapy. Here the authors enhance this cellular network using Flt3L to expand cDC1s and then map the movement of T cells and DCs between tumors and lymph nodes.

Junyun Lai
Cheok Weng Chan
Phillip K. Darcy
ResearchOpen Access10 Feb 2026
Nature Immunology

P: 1-13
Insulin gene region–encoded susceptibility to type 1 diabetes is not restricted to HLA–DR4–positive individuals

S.C. Bain
J.B. Prins
J.A. Todd
Research01 Nov 1992
Nature Genetics

Volume: 2, P: 212-215
Natural selection on protein-coding genes in the human genome

Carlos D. Bustamante
Adi Fledel-Alon
Andrew G. Clark
Research20 Oct 2005
Nature

Volume: 437, P: 1153-1157
Thermal and Photolytic Decomposition of the Lead Azides in Air

G. TODD
E. PARRY
Research20 Oct 1962
Nature

Volume: 196, P: 250-253
Learning neuroimaging models from health system-scale data

Prima is an AI foundation model for neuroimaging based on clinical magnetic resonance imaging that offers accurate and explainable diagnostics, worklist priority for radiologists and clinical referral recommendations with equitable performance on diverse groups.

Yiwei Lyu
Samir Harake
Todd Hollon
Research06 Feb 2026
Nature Biomedical Engineering

P: 1-13
Holistic motor control of zebra finch song syllable sequences

A cortical premotor network in HVC, once initiated, can sustain and regulate the sequential production of zebra finch song syllables without major extrinsic inputs.

Massimo Trusel
Junfeng Zuo
Todd F. Roberts
ResearchOpen Access28 Jan 2026
Nature

P: 1-10
Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332_gp120 glycan-independent epitope

An anti-HIV-1 antibody that targets an N332_gp120 glycan-independent V3 epitope, a site of Env vulnerability, can decline viremia in HIV-1-infected humanized mice while overcoming classical V3 escape mutations.

Lutz Gieselmann
Andrew T. DeLaitsch
Florian Klein
ResearchOpen Access03 Feb 2026
Nature Immunology

P: 1-14
Concentrations of metals in very small volumes of soil solution

Todd Hinkley
Research08 Feb 1979
Nature

Volume: 277, P: 444-446
Structure of Vitamin B₁₂: A Crystalline Nucleotide-Free Degradation Product of Vitamin B₁₂

J. R. CANNON
A. W. JOHNSON
ALEXANDER R. TODD
Research25 Dec 1954
Nature

Volume: 174, P: 1168-1169
Genetics and environment distinctively shape the human immune cell epigenome

A single-cell epigenomic atlas of human immune cells highlights cell-type-specific features associated with genetic or environmental exposures.

Wenliang Wang
Manoj Hariharan
Joseph R. Ecker
ResearchOpen Access27 Jan 2026
Nature Genetics

Volume: 58, P: 392-403
Using the linear references from the pangenome to discover missing autism variants

Large-effect variants in autism remain elusive. Here, the authors use long-read sequencing to assemble phased genomes for 189 individuals, identifying pathogenic variants in TBL1XR1, MECP2, and SYNGAP1, plus nine candidate structural variants missed by short-read methods.

Yang Sui
Jiadong Lin
Evan E. Eichler
ResearchOpen Access23 Jan 2026
Nature Communications

Volume: 17, P: 1-16
MATHEMATICS IN GOVERNMENT SERVICE AND INDUSTRY: Some Deductions from the War-Time Experience of the Admiralty Computing Service*

D. H. SADLER
JOHN TODD
Research04 May 1946
Nature

Volume: 157, P: 571-573
Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells

The xylosyltransferase isoenzymes XT1 and XT2 catalyze the first glycosylation step in the biosynthesis of proteoglycans. Now, bump-and-hole engineering of XT1 and XT2 enables substrate profiling and modification of proteins as designer proteoglycans to modulate cellular behavior.

Zhen Li
Himanshi Chawla
Benjamin Schumann
ResearchOpen Access20 Jan 2026
Nature Chemical Biology

P: 1-10
Ultra-high-throughput mapping of genetic design space

CLASSIC is a high-throughput genetic profiling platform that combines long- and short-read next-generation-sequencing modalities to quantitatively assess pools of constructs of arbitrary length containing diverse genetic part compositions.

Kshitij Rai
Ronan W. O’Connell
Caleb J. Bashor
Research14 Jan 2026
Nature

P: 1-10
Stress vesicles link epidermal mechanotransduction to stem cell differentiation

Using two-photon intravital imaging, the authors show that mechanical stress in skin triggers fluid-filled “stress vesicles” in epidermal cells, altering Piezo1-dependent calcium signals to drive stem cell differentiation and protect tissue integrity.

Sixia Huang
Paola Kuri
Panteleimon Rompolas
ResearchOpen Access23 Jan 2026
Nature Communications

Volume: 17, P: 1-18
Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Lakshmi Raj
Takao Ide
Sam W. Lee
Amendments and Corrections25 Jul 2018
Nature

Volume: 561, P: 420
Chemical Exploration of the Microhabitat by Electron Probe Microanalysis of Decomposer Organisms

ROBERT L. TODD
KERMIT CROMACK
JOHN C. STORMER JUN.
Research29 Jun 1973
Nature

Volume: 243, P: 544-546
Individual and population-level risk factors for new HIV infections among adults in Eastern and Southern Africa

The majority of incident HIV infections in Eastern and Southern Africa occur in the general population. Here, the authors harmonise data from eight open population-based cohort studies from six countries and describe individual and community-level risk factors for HIV acquisition.

Emma Slaymaker
Clara Calvert
Emmanuel Mtuli
ResearchOpen Access06 Jan 2026
Nature Communications

Volume: 17, P: 1-16
Brexanolone infusion produces sustained anti-inflammatory and neurotrophic effects in patients with postpartum depression that predict symptom improvement

Irina Balan
Cecilia Isabel Sousa Pearson
Riah Patterson
ResearchOpen Access31 Jan 2026
Translational Psychiatry

P: 1-12
Genetic diversity of Collaborative Cross mice implicates FFAR3 as a target for ILC2 anti-inflammatory reprogramming

Pulmonary type 2 inflammation is associated with type 2 innate lymphoid cells. Here the authors use the Collaborative Cross mouse panel to show that ILC2 abundance during type 2 lung inflammation is different across the panel and identify free-fatty acid receptor 3 (Ffar3) as a gene responsible and show cytokine and ILC2 functional changes.

Mark Rusznak
Shinji Toki
R. Stokes Peebles Jr
ResearchOpen Access03 Jan 2026
Nature Communications

Volume: 17, P: 1-23
Hydrolysis of Esters of Monoribonucleotides

D. M. BROWN
D. I. MAGRATH
A. R. TODD
Research16 Jun 1956
Nature

Volume: 177, P: 1124-1125
Polygenic control of autoimmune diabetes in nonobese diabetic mice

S. Ghosh
S.M. Palmer
J.A. Todd
Research01 Aug 1993
Nature Genetics

Volume: 4, P: 404-409
Genomic surveillance uncovers regional variation in HCV transmission networks in rural United States

This study explores the genetic structure of hepatitis C virus outbreaks in rural U.S communities affected by the opioid crisis. Analysis of intra-host viral populations from 692 participants reveals hidden transmission networks.

Damien C. Tully
David J. Bean
Todd M. Allen
ResearchOpen Access02 Dec 2025
Nature Communications

Volume: 17, P: 1-16
Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/lty/Bcg genes on chromosome 1

Richard J. Cornall
Jan-Bas Prins
Laurence B. Peterson
Research19 Sept 1991
Nature

Volume: 353, P: 262-265
Direct imaging of the twin QSOs 0957 + 561 A and B: the gravitational lens interpretation

Mark T. Adams
Todd A. Boroson
Research08 Nov 1979
Nature

Volume: 282, P: 183-185
A 3.8 Å resolution cryo-EM structure of a small protein bound to an imaging scaffold

Proteins smaller than about 50 kDa are currently too small to be imaged at high resolution by cryo‐electron microscopy (cryo‐EM). Here authors design a protein scaffold that binds 12 copies of a small 26 kDa protein (GFP), which allowed visualizing GFP at a resolution of 3.8Å by cryo‐EM.

Yuxi Liu
Duc T. Huynh
Todd O. Yeates
ResearchOpen Access23 Apr 2019
Nature Communications

Volume: 10, P: 1-7
Colouring Matters of the Aphididæ

H. DUEWELL
J. P. E. HUMAN
A. R. TODD
Research13 Nov 1948
Nature

Volume: 162, P: 759-761
Rigidity Factor of Gelatin Gels

AUDREY TODD
Research05 Aug 1961
Nature

Volume: 191, P: 567-569
New Horizons in Chemistry

ALEXANDER TODD
Research03 Sept 1960
Nature

Volume: 187, P: 819-824
Genetic analysis of autoimmune type 1 diabetes mellitus in mice

John A. Todd
Timothy J. Aitman
Linda S. Wicker
Research13 Jun 1991
Nature

Volume: 351, P: 542-547
Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis)

J. M. TAYLOR
ANDREE DOZY
D. TODD
Research04 Oct 1974
Nature

Volume: 251, P: 392-393
Structural insights into cauliflower mitoribosome in translation state and in association with a late assembly factor

Plant mitoribosomes are crucial for mitochondrial protein synthesis. Here, authors use cryo-EM to determine high-resolution structures of cauliflower mitoribosomes, and combined with sequencing and mass spectrometry, identified 19 rRNA base modifications.

Vasileios Skaltsogiannis
Philippe Wolff
Florent Waltz
ResearchOpen Access02 Dec 2025
Nature Communications

Volume: 16, P: 1-13
Clinical implications of rare and common variation in preimplantation genetic testing for breast cancer

Todd Lencz
Upasana Bhattacharyya
Shai Carmi
ResearchOpen Access07 Jan 2026
npj Genomic Medicine

Volume: 11, P: 1-5
Wherever we go in this system, there we are

A voyage of discovery.

Todd Honeycutt
Comments & Opinion02 Jul 2025
Nature
Detection of the underlying galaxy in the QSO 3C48

Todd A. Boroson
J. B. Oke
Research01 Apr 1982
Nature

Volume: 296, P: 397-399
Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele

Simon T. Bennett
Amanda J. Wilson
John A. Todd
Research01 Nov 1997
Nature Genetics

Volume: 17, P: 350-352
Cell-cycle arrest versus cell death in cancer therapy

Todd Waldman
Yonggang Zhang
Jerry Williams
Research01 Sept 1997
Nature Medicine

Volume: 3, P: 1034-1036
Foregut microbiome in development of esophageal adenocarcinoma

Carlos Nossa
Fritz Francois
Sukhleen Bedi
ResearchOpen Access19 Oct 2010
Nature Precedings

P: 1
Pre-existing cross-reactive immunity to highly pathogenic avian influenza 2.3.4.4b A(H5N1) virus in the United States

Highly pathogenic avian influenza A H5N1 clade 2.3.4.4b virus has caused outbreaks in dairy cattle and cases in humans in the United States. Here, the authors assess levels of pre-existing cross-reactive antibodies to the epidemic virus strain in human serum samples collected in the United States.

Zhu-Nan Li
Feng Liu
Min Z. Levine
ResearchOpen Access08 Dec 2025
Nature Communications

Volume: 16, P: 1-14
Estimation of genome-wide coupling in rattlesnake hybrids provides insight into the process of speciation and its progress

Genomic coupling theory predicts that speciation progress involves the buildup of genomic associations that manifest in aggregate barriers to gene flow. This study develops approaches to quantify genomic coupling and applies them to a rattlesnake hybrid zone.

Yannick Z. Francioli
Justin M. Bernstein
Todd A. Castoe
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-16
Limitations in PPARα-dependent mitochondrial programming restrain the differentiation of human stem cell-derived β cells

Here they show that PPARα-dependent mitochondrial programming promotes the differentiation of pluripotent stem cell-derived β cells. Targeting mitochondria has the potential to improve β cell replacement efforts for the treatment of type 1 diabetes.

Anne C. Lietzke
Emily M. Walker
Scott A. Soleimanpour
ResearchOpen Access10 Dec 2025
Nature Communications

Volume: 16, P: 1-22
Advanced Instruction in Practical Mathematics

A. ERDÉLYI
JOHN TODD
Research16 Nov 1946
Nature

Volume: 158, P: 690-692
Gene frequencies in Icelandic cats

Neil B Todd
Robert M Fagen
Karen Fagen
Research01 Oct 1975
Heredity

Volume: 35, P: 172-183
Novel coenzyme Q6 genetic variant increases susceptibility to pneumococcal disease

Morley, Pomat and colleagues identify a homozygous mutation in COQ6 in an indigenous population of Papua New Guinea. This allele predisposes children to increased risk of acute lower respiratory infections in response to Streptococcus pneumoniae. This sensitivity is recapitulated in Coq6DY mice in the nonhematopoietic compartment.

Emma C. Walker
Sarah Javati
Sharon Celeste Morley
Research04 Nov 2024
Nature Immunology

Volume: 25, P: 2247-2258
Helping ingredients punch above their weight fraction

Todd Squires highlights the distinction between weight and volume fraction as a conceptual strategy to control the flow and feel of complex fluid products.

Todd M. Squires
Comments & Opinion21 Oct 2025
Nature Chemical Engineering

Volume: 2, P: 663
Aqueous Two-Phase Extraction In Bioseparations: An Assessment

Subhas K. Sikdar
Kenneth D. Cole
Heriberto Cabezas Jr.
Research01 Mar 1991
Bio/Technology

Volume: 9, P: 252-256
Methæmoglobin in Chronic Copper Poisoning of Sheep

J. R. TODD
R. H. THOMPSON
Research01 Jul 1961
Nature

Volume: 191, P: 89-90

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