Nature Search

A subset of transposable elements as mechano-response enhancer elements in controlling human embryonic stem cell fate

Sun et al. identify a subset of transposable elements that serve as mechano-response enhancer elements that control gene expression and human stem cell fate.

Tongyu Sun
Yueyuan Xu
Yarui Diao
Research17 Sept 2025
Nature Cell Biology

P: 1-12
Epigenetic control of topoisomerase 1 activity presents a cancer vulnerability

DNA transactions promote torsional constraints that pose inherent risks to genome integrity. Here the authors identify the macro-histone splice variant macroH2A1.1 as an epigenetic modulator of topoisomerase 1-associated genome maintenance. MacroH2A1.1 expression determines sensitivity to TOP1 poisons and may present a cancer vulnerability.

Tae-Hee Lee
Colina X. Qiao
Philipp Oberdoerffer
ResearchOpen Access12 Aug 2025
Nature Communications

Volume: 16, P: 1-15
Inhibition of ALKBH5 attenuates I/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment

m6A modification has been reported to play roles in many developmental and pathological processes, but its role in AKI remains poorly understood. Here, the authors show the role and the mechanism of the m6A demethylase, ALKBH5 on IRI induced AKI.

Juntao Chen
Cuidi Xu
Tongyu Zhu
ResearchOpen Access01 Mar 2023
Nature Communications

Volume: 14, P: 1-17
Revealing the etching process of water-soluble Au₂₅ nanoclusters at the molecular level

Etching is one of the key considerations in the synthesis, storage, and application of metal nanoparticles. Here, the authors study the etching of water-soluble thiolate-protected gold nanoclusters at a molecular level and reveal an unusual recombination process in the oxidative reaction environment.

Yitao Cao
Tongyu Liu
Jianping Xie
ResearchOpen Access28 May 2021
Nature Communications

Volume: 12, P: 1-7
CHBP induces stronger immunosuppressive CD127⁺ M-MDSC via erythropoietin receptor

Jiawei Li
Guowei Tu
Ruiming Rong
ResearchOpen Access12 Feb 2021
Cell Death & Disease

Volume: 12, P: 1-12
The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice

Interorgan communications play key roles in the regulation of whole-body energy metabolism. Here, the authors report the myokine Musclin as a negative regulator of beige adipose thermogenesis and systemic energy homeostasis through Tfr1/PKA signalling mediated muscle fat crosstalk.

Lu Jin
Shuang Han
Zhuo-Xian Meng
ResearchOpen Access19 Jul 2023
Nature Communications

Volume: 14, P: 1-23
Dynamic X-ray imaging with screen-printed perovskite CMOS array

Biomedical X-ray imaging requires high spatial and temporal resolution of the detectors. Liu et al. report a screen-printed perovskite direct-conversion X-ray CMOS imager with a spatial resolution of 5 lp mm⁻¹ and a speed of 300 fps for low-dose 2D radiography and 3D computed tomography imaging.

Yanliang Liu
Chaosong Gao
Yongshuai Ge
ResearchOpen Access21 Feb 2024
Nature Communications

Volume: 15, P: 1-7
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice

Many transcriptomic pathways in the liver show circadian rhythms, which have been reported to be disrupted in aged mice. Here the authors report that the expression of transcription factor Egr-1 decreases and its rhythm is shifted with age in the liver of male mice, and that deletion of Egr-1 results in increased liver fat accumulation.

Jing Wu
Dandan Bu
Chao-Jun Li
ResearchOpen Access24 Mar 2023
Nature Communications

Volume: 14, P: 1-16
Bolometric-Effect-Based Wavelength-Selective Photodetectors Using Sorted Single Chirality Carbon Nanotubes

Suoming Zhang
Le Cai
Chuan Wang
ResearchOpen Access08 Dec 2015
Scientific Reports

Volume: 5, P: 1-7
Cyclic helix B peptide ameliorates acute myocardial infarction in mice by inhibiting apoptosis and inflammatory responses

Cheng Yang
Chao Zhang
Tongyu Zhu
ResearchOpen Access18 Mar 2019
Cell Death Discovery

Volume: 5, P: 1-10
Genomic features reveal potential benefit of adding anti-PD-1 immunotherapy to treat non-upper aerodigestive tract natural killer/T-cell lymphoma

Zegeng Chen
He Huang
Tongyu Lin
Research20 Feb 2024
Leukemia

Volume: 38, P: 829-839
Ultrathin dual-mode vortex beam generator based on anisotropic coding metasurface

Liang Zhang
Jie Guo
Tongyu Ding
ResearchOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1-8
miR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3

Yunyuan Zhang
Liping Li
Zhijian Qian
ResearchOpen Access25 Apr 2018
Scientific Reports

Volume: 8, P: 1-8
3D field-shaping lens using all-dielectric gradient refractive index materials

Tongyu Ding
Jianjia Yi
Shah Nawaz Burokur
ResearchOpen Access10 Apr 2017
Scientific Reports

Volume: 7, P: 1-8
The transcription factor Foxm1 is essential for the quiescence and maintenance of hematopoietic stem cells

Hematopoietic stem cells are held in check to maintain their functional activity throughout life. Qian and colleagues show that the transcriptional regulator Foxm1 maintains the quiescence and self-renewal capacity of these cells in vivo.

Yu Hou
Wen Li
Zhijian Qian
Research29 Jun 2015
Nature Immunology

Volume: 16, P: 810-818
Weakly supervised chest X-ray abnormality localization with non-linear modulation and foreground control

Tongyu Wang
Kuan Huang
Jianhua Huang
ResearchOpen Access25 Nov 2024
Scientific Reports

Volume: 14, P: 1-13
Long-term tumor-free survival from treatment with the GFP–TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells

Tongyu Lin
Xuefeng Huang
Bingliang Fang
Research13 Nov 2002
Oncogene

Volume: 21, P: 8020-8028
Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Danyang Chong
Yayun Gu
Chaojun Li
ResearchOpen Access11 Oct 2022
Cell Discovery

Volume: 8, P: 1-19
Administration of AG490 decreases the senescence of umbilical cord-mesenchymal stem cells and promotes the cytotherapeutic effect in liver fibrosis

Chenhao Jiang
Huaxin Chen
Yingcai Zhang
ResearchOpen Access28 Jul 2023
Cell Death Discovery

Volume: 9, P: 1-10
Establishing a robust triangulation framework to explore the relationship between hearing loss and Parkinson’s disease

Hao Zhang
Keying Chen
Ping Zeng
ResearchOpen Access03 Jan 2025
npj Parkinson's Disease

Volume: 11, P: 1-12
MSCs ameliorate hepatocellular apoptosis mediated by PINK1-dependent mitophagy in liver ischemia/reperfusion injury through AMPKα activation

Jun Zheng
Liang Chen
Yang Yang
ResearchOpen Access20 Apr 2020
Cell Death & Disease

Volume: 11, P: 1-19
A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo

Jian Gu
Lidong Zhang
Bingliang Fang
Research09 Jul 2002
Oncogene

Volume: 21, P: 4757-4764
Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies

Yingdan Wang
Xiang Zhang
Jinghe Huang
ResearchOpen Access07 Oct 2022
Cell Discovery

Volume: 8, P: 1-15
A proposal for a new staging system for extranodal natural killer T-cell lymphoma: a multicenter study from China and Asia Lymphoma Study Group

Huangming Hong
Yexiong Li
Tongyu Lin
ResearchOpen Access17 Feb 2020
Leukemia

Volume: 34, P: 2243-2248
Hymecromone: a clinical prescription hyaluronan inhibitor for efficiently blocking COVID-19 progression

Shuai Yang
Yun Ling
Hongzhou Lu
ResearchOpen Access18 Mar 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-10
Changes in bacterial community composition in the uterus of Holstein cow with endometritis before and after treatment with oxytetracycline

Xiao-Shi Cai
Hao Jiang
Jia-Bao Zhang
ResearchOpen Access25 Apr 2024
Scientific Reports

Volume: 14, P: 1-11
Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses

Yingdan Wang
Meiqin Liu
Jinghe Huang
ResearchOpen Access21 Apr 2022
Cell Discovery

Volume: 8, P: 1-16
Classification of rice leaf blast severity using hyperspectral imaging

Guosheng Zhang
Tongyu Xu
Zhonghui Guo
ResearchOpen Access17 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
TRPM7 in CHBP-induced renoprotection upon ischemia reperfusion-related injury

Aifen Liu
Jing Wu
Bin Yang
ResearchOpen Access03 Apr 2018
Scientific Reports

Volume: 8, P: 1-14
The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury

Chao Zhang
Shuo Wang
Ruiming Rong
ResearchOpen Access23 Mar 2017
Cell Death & Disease

Volume: 8, P: e2695
Identification and functional characterization of ABCC transporters for Cd tolerance and accumulation in Sedum alfredii Hance

Tongyu Feng
Xuelian He
Mingying Liu
ResearchOpen Access01 Dec 2020
Scientific Reports

Volume: 10, P: 1-13
Smads mediate signaling of the TGFβ superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis

Wei He
Tongyu Cao
Xiao-Jing Wang
Research12 Mar 2001
Oncogene

Volume: 20, P: 471-483
The oncogenic roles and clinical implications of YAP/TAZ in breast cancer

Juan Luo
Hailin Zou
Peng Li
ReviewsOpen Access09 Feb 2023
British Journal of Cancer

Volume: 128, P: 1611-1624
Erythropoietin protects against rhabdomyolysis-induced acute kidney injury by modulating macrophage polarization

Shuo Wang
Chao Zhang
Tongyu Zhu
ResearchOpen Access06 Apr 2017
Cell Death & Disease

Volume: 8, P: e2725
A novel cyclic helix B peptide inhibits dendritic cell maturation during amelioration of acute kidney graft rejection through Jak-2/STAT3/SOCS1

C Yang
Y Zhang
T Zhu
ResearchOpen Access26 Nov 2015
Cell Death & Disease

Volume: 6, P: e1993

Search

A subset of transposable elements as mechano-response enhancer elements in controlling human embryonic stem cell fate

Epigenetic control of topoisomerase 1 activity presents a cancer vulnerability

Inhibition of ALKBH5 attenuates I/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment

Revealing the etching process of water-soluble Au₂₅ nanoclusters at the molecular level

CHBP induces stronger immunosuppressive CD127⁺ M-MDSC via erythropoietin receptor

The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice

Dynamic X-ray imaging with screen-printed perovskite CMOS array

The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice

Bolometric-Effect-Based Wavelength-Selective Photodetectors Using Sorted Single Chirality Carbon Nanotubes

Cyclic helix B peptide ameliorates acute myocardial infarction in mice by inhibiting apoptosis and inflammatory responses

Genomic features reveal potential benefit of adding anti-PD-1 immunotherapy to treat non-upper aerodigestive tract natural killer/T-cell lymphoma

Ultrathin dual-mode vortex beam generator based on anisotropic coding metasurface

miR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3

3D field-shaping lens using all-dielectric gradient refractive index materials

The transcription factor Foxm1 is essential for the quiescence and maintenance of hematopoietic stem cells

Weakly supervised chest X-ray abnormality localization with non-linear modulation and foreground control

Long-term tumor-free survival from treatment with the GFP–TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Administration of AG490 decreases the senescence of umbilical cord-mesenchymal stem cells and promotes the cytotherapeutic effect in liver fibrosis

Establishing a robust triangulation framework to explore the relationship between hearing loss and Parkinson’s disease

MSCs ameliorate hepatocellular apoptosis mediated by PINK1-dependent mitophagy in liver ischemia/reperfusion injury through AMPKα activation

A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo

Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies

A proposal for a new staging system for extranodal natural killer T-cell lymphoma: a multicenter study from China and Asia Lymphoma Study Group

Hymecromone: a clinical prescription hyaluronan inhibitor for efficiently blocking COVID-19 progression

Changes in bacterial community composition in the uterus of Holstein cow with endometritis before and after treatment with oxytetracycline

Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses

Classification of rice leaf blast severity using hyperspectral imaging

TRPM7 in CHBP-induced renoprotection upon ischemia reperfusion-related injury

The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury

Identification and functional characterization of ABCC transporters for Cd tolerance and accumulation in Sedum alfredii Hance

Smads mediate signaling of the TGFβ superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis

The oncogenic roles and clinical implications of YAP/TAZ in breast cancer

Erythropoietin protects against rhabdomyolysis-induced acute kidney injury by modulating macrophage polarization

A novel cyclic helix B peptide inhibits dendritic cell maturation during amelioration of acute kidney graft rejection through Jak-2/STAT3/SOCS1

Search

Quick links

Search

Filter By:

Search

Quick links