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Scientific Reports (4)
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Showing 1–8 of 8 results

Advanced filters: Author: Tony Velkov Clear advanced filters

A novel role for colistin as an efflux pump inhibitor in multidrug-resistant Klebsiella pneumoniae

Rajnikant Sharma
Shekhar Yeshwante
Gauri G. Rao
ResearchOpen Access03 Oct 2025
Scientific Reports

Volume: 15, P: 1-14
A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens

Polymyxins are often the last therapeutic option for multidrug-resistant (MDR) bacteria, but have suboptimal safety and efficacy. Here the authors report the discovery and development of a synthetic lipopeptide with an improved safety and efficacy against top-priority MDR Gram-negative pathogens.

Kade D. Roberts
Yan Zhu
Jian Li
ResearchOpen Access25 Mar 2022
Nature Communications

Volume: 13, P: 1-15
Metabolic profiling unveils enhanced antibacterial synergy of polymyxin B and teixobactin against multi-drug resistant Acinetobacter baumannii

Maytham Hussein
Zhisen Kang
Tony Velkov
ResearchOpen Access07 Nov 2024
Scientific Reports

Volume: 14, P: 1-14
A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity

Zakuan Z Deris
Jesmin Akter
Tony Velkov
Research30 Oct 2013
The Journal of Antibiotics

Volume: 67, P: 147-151
Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis

Chongshan Dai
Xilong Xiao
Shusheng Tang
ResearchOpen Access26 Nov 2018
Cell Death & Disease

Volume: 9, P: 1-13
Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii

Mohd Hafidz Mahamad Maifiah
Darren J. Creek
Jian Li
ResearchOpen Access30 Mar 2017
Scientific Reports

Volume: 7, P: 1-12
Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

Mohd Hafidz Mahamad Maifiah
Soon-Ee Cheah
Jian Li
ResearchOpen Access29 Feb 2016
Scientific Reports

Volume: 6, P: 1-17
Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii

Thien B Tran
Soon-Ee Cheah
Jian Li
Research16 Dec 2015
The Journal of Antibiotics

Volume: 69, P: 415-421