CD271, also known as nerve growth factor receptor, is expressed in lung, penile, vulvar, and esophageal squamous carcinoma, but not in lung adenocarcinoma. This study determined that cell proliferation in lung squamous cell carcinoma depends on CD271, suggesting that siRNA against CD271 is a potential therapeutic strategy for certain cancers.
- Mai Mochizuki
- Mao Nakamura
- Keiichi Tamai